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Role of L-carnitine in female infertility

Overview of attention for article published in Reproductive Biology and Endocrinology, January 2018
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  • Good Attention Score compared to outputs of the same age (67th percentile)

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5 tweeters
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1 Facebook page

Citations

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16 Dimensions

Readers on

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79 Mendeley
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Title
Role of L-carnitine in female infertility
Published in
Reproductive Biology and Endocrinology, January 2018
DOI 10.1186/s12958-018-0323-4
Pubmed ID
Authors

Ashok Agarwal, Pallav Sengupta, Damayanthi Durairajanayagam

Abstract

L-carnitine (LC), and its acetylated form, acetyl L-carnitine (ALC), have immense functional capabilities to regulate the oxidative and metabolic status of the female reproductive system. The vulnerability of this system to free radicals demand for advanced strategies to combat them. For this purpose, the 'quasi vitamins' LC and ALC can be used either individually, or in combination with each other or with other antioxidants. This review (a) summarizes the effects of carnitines on female fertility along with the findings from various in vivo and in vitro studies involving human, animal and assisted reproductive technology, and (b) proposes their mechanism of actions in improving female fertility through their integrated actions on reducing cellular stress, maintaining hormonal balance and enhancing energy production. They reportedly aid β-oxidation in oocytes, maintain its cell membrane stability by acetylation of phospholipids and amphiphilic actions, prevent free radical-induced DNA damage and also stabilize acetyl Co-A/Co-A ratio for adequate acetyl storage as energy supply to maintain the robustness of reproductive cells. While both LC and ALC have their applications in improving female fertility, ALC is preferred for its better antioxidant properties and LC for amelioration of energy supply to the cells. These beneficial effects show great promise in its application as a treatment option for women facing infertility disorders.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 79 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 14%
Student > Bachelor 10 13%
Researcher 10 13%
Student > Ph. D. Student 7 9%
Other 6 8%
Other 19 24%
Unknown 16 20%
Readers by discipline Count As %
Medicine and Dentistry 21 27%
Agricultural and Biological Sciences 9 11%
Biochemistry, Genetics and Molecular Biology 8 10%
Veterinary Science and Veterinary Medicine 6 8%
Nursing and Health Professions 3 4%
Other 10 13%
Unknown 22 28%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2020.
All research outputs
#4,619,380
of 16,019,740 outputs
Outputs from Reproductive Biology and Endocrinology
#179
of 635 outputs
Outputs of similar age
#119,237
of 369,025 outputs
Outputs of similar age from Reproductive Biology and Endocrinology
#1
of 1 outputs
Altmetric has tracked 16,019,740 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 635 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 369,025 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them