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Temperature Dependence of Erythromelalgia Mutation L858F in Sodium Channel Nav1.7

Overview of attention for article published in Molecular Pain, January 2007
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)

Mentioned by

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2 Facebook pages
wikipedia
1 Wikipedia page

Citations

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40 Dimensions

Readers on

mendeley
44 Mendeley
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Title
Temperature Dependence of Erythromelalgia Mutation L858F in Sodium Channel Nav1.7
Published in
Molecular Pain, January 2007
DOI 10.1186/1744-8069-3-3
Pubmed ID
Authors

Chongyang Han, Angelika Lampert, Anthony M Rush, Sulayman D Dib-Hajj, Xiaoliang Wang, Yong Yang, Stephen G Waxman

Abstract

The disabling chronic pain syndrome erythromelalgia (also termed erythermalgia) is characterized by attacks of burning pain in the extremities induced by warmth. Pharmacological treatment is often ineffective, but the pain can be alleviated by cooling of the limbs. Inherited erythromelalgia has recently been linked to mutations in the gene SCN9A, which encodes the voltage-gated sodium channel Nav1.7. Nav1.7 is preferentially expressed in most nociceptive DRG neurons and in sympathetic ganglion neurons. It has recently been shown that several disease-causing erythromelalgia mutations alter channel-gating behavior in a manner that increases DRG neuron excitability.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Switzerland 1 2%
Unknown 43 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 27%
Student > Ph. D. Student 9 20%
Professor 6 14%
Student > Master 5 11%
Student > Bachelor 4 9%
Other 4 9%
Unknown 4 9%
Readers by discipline Count As %
Medicine and Dentistry 10 23%
Agricultural and Biological Sciences 8 18%
Neuroscience 7 16%
Pharmacology, Toxicology and Pharmaceutical Science 4 9%
Engineering 4 9%
Other 5 11%
Unknown 6 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 May 2019.
All research outputs
#7,960,052
of 25,374,647 outputs
Outputs from Molecular Pain
#168
of 669 outputs
Outputs of similar age
#44,421
of 173,002 outputs
Outputs of similar age from Molecular Pain
#2
of 3 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 173,002 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.