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miRNA as a New Regulatory Mechanism of Estrogen Vascular Action

Overview of attention for article published in International Journal of Molecular Sciences, February 2018
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1 tweeter

Citations

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Readers on

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40 Mendeley
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Title
miRNA as a New Regulatory Mechanism of Estrogen Vascular Action
Published in
International Journal of Molecular Sciences, February 2018
DOI 10.3390/ijms19020473
Pubmed ID
Authors

Daniel Pérez-Cremades, Ana Mompeón, Xavier Vidal-Gómez, Carlos Hermenegildo, Susana Novella

Abstract

The beneficial effects of estrogen on the cardiovascular system have been reported extensively. In fact, the incidence of cardiovascular diseases in women is lower than in age-matched men during their fertile stage of life, a benefit that disappears after menopause. These sex-related differences point to sexual hormones, mainly estrogen, as possible cardiovascular protective factors. The regulation of vascular function by estrogen is mainly related to the maintenance of normal endothelial function and is mediated by both direct and indirect gene transcription through the activity of specific estrogen receptors. Some of these mechanisms are known, but many remain to be elucidated. In recent years, microRNAs have been established as non-coding RNAs that regulate the expression of a high percentage of protein-coding genes in mammals and are related to the correct function of human physiology. Moreover, within the cardiovascular system, miRNAs have been related to physiological and pathological conditions. In this review, we address what is known about the role of estrogen-regulated miRNAs and their emerging involvement in vascular biology.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 40 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 25%
Student > Master 8 20%
Student > Ph. D. Student 6 15%
Other 3 8%
Student > Bachelor 2 5%
Other 4 10%
Unknown 7 18%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 12 30%
Agricultural and Biological Sciences 3 8%
Medicine and Dentistry 3 8%
Computer Science 2 5%
Sports and Recreations 2 5%
Other 3 8%
Unknown 15 38%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2018.
All research outputs
#11,094,120
of 12,476,917 outputs
Outputs from International Journal of Molecular Sciences
#6,676
of 8,725 outputs
Outputs of similar age
#287,766
of 339,979 outputs
Outputs of similar age from International Journal of Molecular Sciences
#380
of 528 outputs
Altmetric has tracked 12,476,917 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,725 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 339,979 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 528 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.