Title |
Food protein-induced enterocolitis syndrome: a review of the new guidelines
|
---|---|
Published in |
World Allergy Organization Journal, February 2018
|
DOI | 10.1186/s40413-017-0182-z |
Pubmed ID | |
Authors |
Stephanie A. Leonard, Valentina Pecora, Alessandro Giovanni Fiocchi, Anna Nowak-Wegrzyn |
Abstract |
Food protein-induced enterocolitis syndrome (FPIES) is a non IgE-mediated gastrointestinal food allergy that presents with delayed vomiting after ingestion primarily in infants. While the pathophysiology of FPIES is poorly understood, the clinical presentation of acute FPEIS reactions has been well characterized. The firstInternational Consensus Guidelines for the Diagnosis and Management of Food Protein-induced Enterocolitis Syndromewere published in 2017 and reviewed epidemiology, clinical presentation, and prognosis of acute and chronic FPIES. The workgroup outlined clinical phenotypes, proposed diagnostic criteria, and made recommendations on management. This article summarizes the guidelines and adds recent updates. FPIES is gaining recognition, however there continues to be delays in diagnosis and misdiagnosis due to overlap of symptoms with over conditions, lack of a diagnostic test, and because some of the common trigger foods are not thought of as allergenic. More research into disease mechanisms and factors influencing differences between populations is needed. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 7 | 13% |
Spain | 6 | 11% |
Mexico | 6 | 11% |
United Kingdom | 4 | 7% |
Colombia | 2 | 4% |
Canada | 2 | 4% |
Egypt | 1 | 2% |
Ireland | 1 | 2% |
Australia | 1 | 2% |
Other | 5 | 9% |
Unknown | 20 | 36% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 41 | 75% |
Practitioners (doctors, other healthcare professionals) | 9 | 16% |
Scientists | 5 | 9% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 125 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 19 | 15% |
Other | 16 | 13% |
Researcher | 9 | 7% |
Student > Master | 8 | 6% |
Professor > Associate Professor | 7 | 6% |
Other | 15 | 12% |
Unknown | 51 | 41% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 40 | 32% |
Nursing and Health Professions | 9 | 7% |
Biochemistry, Genetics and Molecular Biology | 8 | 6% |
Agricultural and Biological Sciences | 4 | 3% |
Immunology and Microbiology | 3 | 2% |
Other | 9 | 7% |
Unknown | 52 | 42% |