↓ Skip to main content

The interaction of selenoprotein F (SELENOF) with retinol dehydrogenase 11 (RDH11) implied a role of SELENOF in vitamin A metabolism

Overview of attention for article published in Nutrition & Metabolism, January 2018
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
12 Dimensions

Readers on

mendeley
10 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
The interaction of selenoprotein F (SELENOF) with retinol dehydrogenase 11 (RDH11) implied a role of SELENOF in vitamin A metabolism
Published in
Nutrition & Metabolism, January 2018
DOI 10.1186/s12986-017-0235-x
Pubmed ID
Authors

Jing Tian, Jiapan Liu, Jieqiong Li, Jingxin Zheng, Lifang Chen, Yujuan Wang, Qiong Liu, Jiazuan Ni

Abstract

Selenoprotein F (SELENOF, was named as 15-kDa selenoprotein) has been reported to play important roles in oxidative stress, endoplasmic reticulum (ER) stress and carcinogenesis. However, the biological function of SELENOF is still unclear. A yeast two-hybrid system was used to screen the interactive protein of SELENOF in a human fetal brain cDNA library. The interaction between SELENOF and interactive protein was validated by fluorescence resonance energy transfer (FRET), co-immunoprecipitation (co-IP) and pull-down assays. The production of retinol was detected by high performance liquid chromatograph (HPLC). Retinol dehydrogenase 11 (RDH11) was found to interact with SELENOF. RDH11 is an enzyme for the reduction of all-trans-retinaldehyde to all-trans-retinol (vitamin A). The production of retinol was decreased by SELENOF overexpression, resulting in more retinaldehyde. SELENOF interacts with RDH11 and blocks its enzyme activity to reduce all-trans-retinaldehyde.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Lecturer 1 10%
Student > Doctoral Student 1 10%
Professor 1 10%
Student > Master 1 10%
Researcher 1 10%
Other 0 0%
Unknown 5 50%
Readers by discipline Count As %
Agricultural and Biological Sciences 2 20%
Biochemistry, Genetics and Molecular Biology 1 10%
Environmental Science 1 10%
Business, Management and Accounting 1 10%
Chemistry 1 10%
Other 0 0%
Unknown 4 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 February 2018.
All research outputs
#18,585,544
of 23,020,670 outputs
Outputs from Nutrition & Metabolism
#775
of 950 outputs
Outputs of similar age
#330,377
of 441,092 outputs
Outputs of similar age from Nutrition & Metabolism
#17
of 19 outputs
Altmetric has tracked 23,020,670 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 950 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.7. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 441,092 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.