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A comprehensive review of the safety and efficacy of bioidentical hormones for the management of menopause and related health risks.

Overview of attention for article published in Alternative Medicine Review, January 2007
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (68th percentile)

Mentioned by

wikipedia
1 Wikipedia page

Citations

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36 Dimensions

Readers on

mendeley
79 Mendeley
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Title
A comprehensive review of the safety and efficacy of bioidentical hormones for the management of menopause and related health risks.
Published in
Alternative Medicine Review, January 2007
Pubmed ID
Authors

Moskowitz D

Abstract

Numerous forms of estrogens and progestins are utilized for the treatment of menopausal complaints and associated conditions that occur temporally. Although known to be different with respect to molecular structure, receptor affinity, metabolism, and other physiological traits, most have been treated as if they were clinically identical. The majority of these hormone preparations, commonly referred to as hormone replacement therapy (HRT), should perhaps be more aptly referred to as hormone substitution therapy, as most of the therapies utilized do not exactly match those produced in the body. Research indicates these synthetic hormones vary clinically in safety and efficacy. As such, women and their physicians have, in increasing numbers, been opting for the use of bioidentical hormones; i.e., those that match the structure and function of hormones produced in the body. With greater utilization and research surrounding bioidentical hormones, the differences can now begin to be fully assessed and appreciated. This article reviews the disparities between synthetic and bioidentical estrogens and progestins/progesterone with respect to safety and efficacy; special attention is devoted to clinical outcomes in the breast, endometrium, bone, cardiovascular system, and brain. The studies reviewed suggest bioidentical progesterone does not have a negative effect on blood lipids or vasculature as do many synthetic progestins, and may carry less risk with respect to breast cancer incidence. Studies of both bioidentical estrogens and progesterone suggest a reduced risk of blood clots compared to non-bioidentical preparations. Bioidentical hormone preparations have demonstrated effectiveness in addressing menopausal symptoms. The author advocates for continued research on bioidentical hormones and concludes there is currently sufficient evidence to support their preferred use over that of their synthetic cousins.

Mendeley readers

The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 6%
Unknown 74 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 22%
Student > Master 9 11%
Other 8 10%
Student > Postgraduate 8 10%
Student > Doctoral Student 6 8%
Other 26 33%
Unknown 5 6%
Readers by discipline Count As %
Medicine and Dentistry 38 48%
Agricultural and Biological Sciences 13 16%
Nursing and Health Professions 5 6%
Neuroscience 3 4%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Other 10 13%
Unknown 7 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 August 2016.
All research outputs
#2,102,286
of 8,243,836 outputs
Outputs from Alternative Medicine Review
#88
of 169 outputs
Outputs of similar age
#69,148
of 240,487 outputs
Outputs of similar age from Alternative Medicine Review
#1
of 1 outputs
Altmetric has tracked 8,243,836 research outputs across all sources so far. This one has received more attention than most of these and is in the 60th percentile.
So far Altmetric has tracked 169 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.7. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,487 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them