Title |
Being treated in higher volume hospitals leads to longer progression-free survival for epithelial ovarian carcinoma patients in the Rhone-Alpes region of France
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Published in |
BMC Health Services Research, January 2018
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DOI | 10.1186/s12913-017-2802-2 |
Pubmed ID | |
Authors |
Marius Huguet, Lionel Perrier, Olivia Bally, David Benayoun, Pierre De Saint Hilaire, Dominique Beal Ardisson, Magali Morelle, Nathalie Havet, Xavier Joutard, Pierre Meeus, Philippe Gabelle, Jocelyne Provençal, Céline Chauleur, Olivier Glehen, Amandine Charreton, Fadila Farsi, Isabelle Ray-Coquard |
Abstract |
To investigate the relationship between hospital volume activities and the survival for Epithelial Ovarian Carcinoma (EOC) patients in France. This retrospective study using prospectively implemented databases was conducted on an exhaustive cohort of 267 patients undergoing first-line therapy during 2012 in the Rhone-Alpes Region of France. We compared Progression-Free Survival for Epithelial Ovarian Carcinoma patients receiving first-line therapy in high- (i.e. ≥ 12 cases/year) vs. low-volume hospitals. To control for selection bias, multivariate analysis and propensity scores were used. An adjusted Kaplan-Meier estimator and a univariate Cox model weighted by the propensity score were applied. Patients treated in the low-volume hospitals had a probability of relapse (including death) that was almost two times (i.e. 1.94) higher than for patients treated in the high-volume hospitals (p < 0.001). To our knowledge, this is the first study conducted in this setting in France. As reported in other countries, there was a significant positive association between greater volume of hospital care for EOC and patient survival. Other factors may also be important such as the quality of the surgical resection. |
X Demographics
Geographical breakdown
Country | Count | As % |
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France | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 5 | 28% |
Student > Bachelor | 3 | 17% |
Other | 2 | 11% |
Student > Ph. D. Student | 1 | 6% |
Student > Doctoral Student | 1 | 6% |
Other | 0 | 0% |
Unknown | 6 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 4 | 22% |
Economics, Econometrics and Finance | 2 | 11% |
Nursing and Health Professions | 1 | 6% |
Social Sciences | 1 | 6% |
Earth and Planetary Sciences | 1 | 6% |
Other | 0 | 0% |
Unknown | 9 | 50% |