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Polyglutamine Disorders

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Cover of 'Polyglutamine Disorders'

Table of Contents

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    Book Overview
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    Chapter 1 Clinical Features of Huntington’s Disease
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    Chapter 2 Genetic Rodent Models of Huntington Disease
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    Chapter 3 Mitochondrial Dysfunction in Huntington’s Disease
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    Chapter 4 RNA Related Pathology in Huntington’s Disease
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    Chapter 5 X-Linked Spinal and Bulbar Muscular Atrophy: From Clinical Genetic Features and Molecular Pathology to Mechanisms Underlying Disease Toxicity
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    Chapter 6 Spinocerebellar Ataxia Type 1: Molecular Mechanisms of Neurodegeneration and Preclinical Studies
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    Chapter 7 Spinocerebellum Ataxia Type 6: Molecular Mechanisms and Calcium Channel Genetics
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    Chapter 8 Spinocerebellar Ataxia Type 2
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    Chapter 9 Molecular Mechanisms and Therapeutic Strategies in Spinocerebellar Ataxia Type 7
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    Chapter 10 Spinocerebellar Ataxia Type 17 (SCA17)
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    Chapter 11 The Neuropathology of Spinocerebellar Ataxia Type 3/Machado-Joseph Disease
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    Chapter 12 Origins and Spread of Machado-Joseph Disease Ancestral Mutations Events
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    Chapter 13 Clinical Features of Machado-Joseph Disease
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    Chapter 14 Polyglutamine-Independent Features in Ataxin-3 Aggregation and Pathogenesis of Machado-Joseph Disease
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    Chapter 15 Animal Models of Machado-Joseph Disease
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    Chapter 16 Towards the Identification of Molecular Biomarkers of Spinocerebellar Ataxia Type 3 (SCA3)/Machado-Joseph Disease (MJD)
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    Chapter 17 Planning Future Clinical Trials for Machado-Joseph Disease
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    Chapter 18 Molecular Mechanisms and Cellular Pathways Implicated in Machado-Joseph Disease Pathogenesis
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    Chapter 19 Pharmacological Therapies for Machado-Joseph Disease
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    Chapter 20 Gene Therapies for Polyglutamine Diseases
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    Chapter 21 Stem Cell-Based Therapies for Polyglutamine Diseases
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