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Glycosylation, transport, and complex formation of palmitoyl protein thioesterase 1 (PPT1) – distinct characteristics in neurons

Overview of attention for article published in BMC Cell Biology, June 2007
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1 Wikipedia page

Citations

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39 Mendeley
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Title
Glycosylation, transport, and complex formation of palmitoyl protein thioesterase 1 (PPT1) – distinct characteristics in neurons
Published in
BMC Cell Biology, June 2007
DOI 10.1186/1471-2121-8-22
Pubmed ID
Authors

Annina Lyly, Carina von Schantz, Tarja Salonen, Outi Kopra, Jani Saarela, Matti Jauhiainen, Aija Kyttälä, Anu Jalanko

Abstract

Neuronal ceroid lipofuscinoses (NCLs) are collectively the most common type of recessively inherited childhood encephalopathies. The most severe form of NCL, infantile neuronal ceroid lipofuscinosis (INCL), is caused by mutations in the CLN1 gene, resulting in a deficiency of the lysosomal enzyme, palmitoyl protein thioesterase 1 (PPT1). The deficiency of PPT1 causes a specific death of neocortical neurons by a mechanism, which is currently unclear. To understand the function of PPT1 in more detail, we have further analyzed the basic properties of the protein, especially focusing on possible differences in non-neuronal and neuronal cells.

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Unknown 38 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 33%
Student > Ph. D. Student 9 23%
Student > Bachelor 4 10%
Other 2 5%
Student > Postgraduate 2 5%
Other 5 13%
Unknown 4 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 28%
Medicine and Dentistry 8 21%
Biochemistry, Genetics and Molecular Biology 4 10%
Chemistry 3 8%
Neuroscience 3 8%
Other 3 8%
Unknown 7 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2008.
All research outputs
#7,453,350
of 22,786,087 outputs
Outputs from BMC Cell Biology
#78
of 313 outputs
Outputs of similar age
#24,798
of 70,065 outputs
Outputs of similar age from BMC Cell Biology
#2
of 4 outputs
Altmetric has tracked 22,786,087 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 313 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 70,065 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.