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Mendeley readers
Attention Score in Context
| Title |
A Novel Mammalian Iron-regulated Protein Involved in Intracellular Iron Metabolism*
|
|---|---|
| Published in |
Journal of Biological Chemistry, June 2000
|
| DOI | 10.1074/jbc.m000713200 |
| Pubmed ID | |
| Authors |
Sherry Abboud, David J. Haile |
| Abstract |
We have isolated and characterized a novel iron-regulated gene that is homologous to the divalent metal transporter 1 family of metal transporters. This gene, termed metal transporter protein (mtp1), is expressed in tissues involved in body iron homeostasis including the developing and mature reticuloendothelial system, the duodenum, and the pregnant uterus. MTP1 is also expressed in muscle and central nervous system cells in the embryo. At the subcellular level, MTP1 is localized to the basolateral membrane of the duodenal epithelial cell and a cytoplasmic compartment of reticuloendothelial system cells. Overexpression of MTP1 in tissue culture cells results in intracellular iron depletion. In the adult mouse, MTP1 expression in the liver and duodenum are reciprocally regulated. Iron deficiency induces MTP1 expression in the duodenum but down-regulates expression in the liver. These data indicate that MTP1 is an iron-regulated membrane-spanning protein that is involved in intracellular iron metabolism. |
Mendeley readers
The data shown below were compiled from readership statistics for 303 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Italy | 1 | <1% |
| Korea, Republic of | 1 | <1% |
| Unknown | 300 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 56 | 18% |
| Student > Master | 43 | 14% |
| Researcher | 35 | 12% |
| Student > Bachelor | 33 | 11% |
| Student > Doctoral Student | 27 | 9% |
| Other | 52 | 17% |
| Unknown | 57 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 73 | 24% |
| Biochemistry, Genetics and Molecular Biology | 64 | 21% |
| Medicine and Dentistry | 48 | 16% |
| Chemistry | 13 | 4% |
| Neuroscience | 7 | 2% |
| Other | 36 | 12% |
| Unknown | 62 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 June 2023.
All research outputs
#2,863,855
of 25,374,647 outputs
Outputs from Journal of Biological Chemistry
#3,157
of 85,241 outputs
Outputs of similar age
#2,327
of 39,990 outputs
Outputs of similar age from Journal of Biological Chemistry
#13
of 754 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 85,241 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 39,990 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 754 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.