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Hypertonic saline infusion for treating intracranial hypertension after severe traumatic brain injury

Overview of attention for article published in Critical Care, February 2018
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

Mentioned by

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57 X users
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3 Facebook pages
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1 Google+ user

Citations

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27 Dimensions

Readers on

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93 Mendeley
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Title
Hypertonic saline infusion for treating intracranial hypertension after severe traumatic brain injury
Published in
Critical Care, February 2018
DOI 10.1186/s13054-018-1963-7
Pubmed ID
Authors

Halinder S. Mangat

Abstract

Traumatic brain injury (TBI) remains a major cause of mortality and disability. Post-traumatic intracranial hypertension (ICH) further complicates the care of patients. Hyperosmolar agents are recommended for the treatment of ICH, but no consensus or high-level data exist on the use of any particular agent or the route of administration. The two agents used commonly are hypertonic saline (HTS) and mannitol given as bolus therapy. Smaller studies suggest that HTS may be a superior agent in reducing the ICH burden, but neither agent has been shown to improve mortality or functional outcome. In a recently published analysis of pooled data from three prospective clinical trials, continuous infusion of HTS correlated with serum hypernatremia and reduced ICH burden in addition to improving 90-day mortality and functional outcome. This lays the foundation for the upcoming continuous hyperosmolar therapy for traumatic brain-injured patients (COBI) randomized controlled trial to study the outcome benefit of continuous HTS infusion to treat ICH after severe TBI. This is much anticipated and will be a high impact trial should the results be replicated. However, this would still leave a question over the use of mannitol bolus therapy which will need to be studied.

X Demographics

X Demographics

The data shown below were collected from the profiles of 57 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 93 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 14 15%
Student > Postgraduate 11 12%
Other 8 9%
Student > Master 8 9%
Professor > Associate Professor 7 8%
Other 20 22%
Unknown 25 27%
Readers by discipline Count As %
Medicine and Dentistry 39 42%
Nursing and Health Professions 12 13%
Psychology 4 4%
Neuroscience 2 2%
Engineering 2 2%
Other 4 4%
Unknown 30 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 37. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 February 2022.
All research outputs
#1,097,139
of 25,468,708 outputs
Outputs from Critical Care
#877
of 6,567 outputs
Outputs of similar age
#24,459
of 344,553 outputs
Outputs of similar age from Critical Care
#33
of 84 outputs
Altmetric has tracked 25,468,708 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,567 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,553 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.