You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Attention Score in Context
| Title |
The dimerization domain of HIV-1 viral infectivity factor Vif is required to block virion incorporation of APOBEC3G
|
|---|---|
| Published in |
Retrovirology, November 2007
|
| DOI | 10.1186/1742-4690-4-81 |
| Pubmed ID | |
| Authors |
James H Miller, Vlad Presnyak, Harold C Smith |
| Abstract |
The HIV-1 accessory protein known as viral infectivity factor or Vif binds to the host defence factor human APOBEC3G (hA3G) and prevents its assembly with viral particles and mediates its elimination through ubiquitination and degradation by the proteosomal pathway. In the absence of Vif, hA3G becomes incorporated within viral particles. During the post entry phase of infection, hA3G attenuates viral replication by binding to the viral RNA genome and deaminating deoxycytidines to form deoxyuridines within single stranded DNA regions of the replicated viral genome. Vif dimerization has been reported to be essential for viral infectivity but the mechanistic requirement for Vif multimerization is unknown. |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 5% |
| Brazil | 3 | 5% |
| France | 1 | 2% |
| Spain | 1 | 2% |
| Unknown | 51 | 86% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 25% |
| Researcher | 14 | 24% |
| Student > Bachelor | 7 | 12% |
| Student > Master | 7 | 12% |
| Student > Doctoral Student | 3 | 5% |
| Other | 10 | 17% |
| Unknown | 3 | 5% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 31 | 53% |
| Chemistry | 7 | 12% |
| Biochemistry, Genetics and Molecular Biology | 7 | 12% |
| Medicine and Dentistry | 3 | 5% |
| Nursing and Health Professions | 1 | 2% |
| Other | 6 | 10% |
| Unknown | 4 | 7% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 June 2014.
All research outputs
#7,453,350
of 22,786,087 outputs
Outputs from Retrovirology
#408
of 1,106 outputs
Outputs of similar age
#41,116
of 156,521 outputs
Outputs of similar age from Retrovirology
#8
of 18 outputs
Altmetric has tracked 22,786,087 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,106 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 156,521 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.