@Rafael_Narbona https://t.co/1HQLZAt8Ul Decir que la depresión es un desorden bioquímico es tan científicamente falso como que los antidepresivos son un placebo. El psicologicismo es tan peligroso como en el biologicismo, todo es mucho más complejo.
Les antidépresseurs sont efficaces (voir par exemple https://t.co/dc9LpvPjU0). Pas autant qu'on le souhaiterait mais ils le sont. Sous-entendre l'inverse est dangereux en termes de santé publique.
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
Melhor estudo que eu encontrei: https://t.co/4EpeWsaN1c Bula do profissional de saúde: https://t.co/ExQAdJdLYB Agomelatina é o antidepressivo mais bem aceitado e tolerado pelos pacientes, sem abandonos de tratamento: https://t.co/KgxkMQ8Vt6
@GiovaVivas @Catarsisp Ahora, que no se entienda a cabalidad el mecanismo de acción de un fármaco no limita su utilidad clínica (p ej, acetaminofén, litio, fenitoína, metformina...). La eficacia de los antidepresivos es innegable: https://t.co/W22aOap6BG
@HaydnWestDoP @PsychSleepy Not that @TheLancet is infallible (Andrew Wakefield etc) but this meta-analysis is a decent place to start. https://t.co/NrN82TeonZ
RT @carlos_arnaud: Lo invito a revisar el meta-análisis más grande publicado sobre la eficacia de los antidepresivos en depresión Con más d…
@juanfranciscomo @leidymarmalade Para que se instruya un poquito: https://t.co/W22aOap6BG https://t.co/k9b6znwRlo
RT @carlos_arnaud: Lo invito a revisar el meta-análisis más grande publicado sobre la eficacia de los antidepresivos en depresión Con más d…
RT @carlos_arnaud: Lo invito a revisar el meta-análisis más grande publicado sobre la eficacia de los antidepresivos en depresión Con más d…
RT @AlfredoLopPce: https://t.co/YoAwQObHej Aquí un meta-análisis de 522 estudios "head-to-head" o controlados con placebo, aleatorizados y…
... "All antidepressants were more efficacious than placebo in adults with major depressive disorder."... https://t.co/o2VuJgGEOp
RT @AlfredoLopPce: https://t.co/YoAwQObHej Aquí un meta-análisis de 522 estudios "head-to-head" o controlados con placebo, aleatorizados y…
RT @carlos_arnaud: Lo invito a revisar el meta-análisis más grande publicado sobre la eficacia de los antidepresivos en depresión Con más d…
RT @carlos_arnaud: Lo invito a revisar el meta-análisis más grande publicado sobre la eficacia de los antidepresivos en depresión Con más d…
RT @AlfredoLopPce: https://t.co/YoAwQObHej Aquí un meta-análisis de 522 estudios "head-to-head" o controlados con placebo, aleatorizados y…
RT @carlos_arnaud: Lo invito a revisar el meta-análisis más grande publicado sobre la eficacia de los antidepresivos en depresión Con más d…
Lo invito a revisar el meta-análisis más grande publicado sobre la eficacia de los antidepresivos en depresión Con más de 116 mil pacientes, donde se demuestra que el antidepresivo es más eficaz que el placebo No hay duda que los antidepresivos funcionan h
Esto. Para que no dejen de tomar sus medicinas porque un terraplanista progre quiere ganar unos likes.
RT @AlfredoLopPce: https://t.co/YoAwQObHej Aquí un meta-análisis de 522 estudios "head-to-head" o controlados con placebo, aleatorizados y…
RT @AlfredoLopPce: https://t.co/YoAwQObHej Aquí un meta-análisis de 522 estudios "head-to-head" o controlados con placebo, aleatorizados y…
https://t.co/YoAwQObHej Aquí un meta-análisis de 522 estudios "head-to-head" o controlados con placebo, aleatorizados y doble-ciego. Pero este bembo subnormal no sabe qué es eso. No tendría por qué saberlo. Él no.
@doctorid @JrQuepu @And_Cipriani And here's what Cipriani et al. found regarding when analyzing the contribution of pharmaceutical study sponsorship (in the appendix data of the study)... that antidepressants were still superior to placebo. https://t.co/5
@vortuosity @Nukapai @TunaEmren Yeah. 1. The mechanism of action for the anti depressants remains to be elucidated. 2. Systematic network meta analysis of 522 studies, all depressants have an effect greater vs placebo, with effect sizes (odds ratios) rangi
RT @mbahndi: salah satu contoh tulisannya ini hanya mengambil sejumlah kecil perbandigan dengan placebo (tidak ada referensinya) pdhl di ju…
@racioaberto @EliVieiraJr Lembrando que serotonina é só um dos vários neurotransmissores. Esse artigo é muito bom. A Agomelatina é tida como o melhor antidepressivo em termos de aceitabilidade. Aliás, possui mecanismo de ação único: regula o ritmo circadi
@JonathanShedler Unfortunately, meta-analyses also include "spin" and depending on how they are performed can show markedly different effect sizes. For instance, antidepressants fair quite well in this thorough analysis that focuses on odds of meaningful r
Comparing various antidepressants' usefulness in treating depression modelled as being caused by a neurotransmitter dysfunction. Simplistic idea discounting the individual's lived experience, mental fitness/health, and psychology. Pills are cheap though h
One study showed 29 of 32 comparisons with placebo detected an antidepressant signal from the tested SSRI. (https://t.co/R9xt4Cdh6m) Another surveyed 522 trials with 116k participants and concluded all antidepressants were more efficacious than placebo. (
RT @mbahndi: salah satu contoh tulisannya ini hanya mengambil sejumlah kecil perbandigan dengan placebo (tidak ada referensinya) pdhl di ju…
RT @mbahndi: salah satu contoh tulisannya ini hanya mengambil sejumlah kecil perbandigan dengan placebo (tidak ada referensinya) pdhl di ju…
salah satu contoh tulisannya ini hanya mengambil sejumlah kecil perbandigan dengan placebo (tidak ada referensinya) pdhl di jurnal yg diakui spt Lancet : "All antidepressants were more efficacious than placebo in adults with major depressive disorder." htt
*THANK YOU*
@Barbusceptique @futurasciences J'étais personnellement resté là dessus (2018) : https://t.co/pnd7qAlOLf Commenté ici https://t.co/07rKxYZdJY
RT @allyrooney: Cue media hysteria with articles or headlines, reporting this study, implying that 'antidepressants are not grounded in sci…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
@xanalysis @VeritasLos @susan_dolma @HeinzGHerzog3 @sonmuda ja klar. Hier die grösste und neueste bisher durchgefeführte Metastudie. Gab da natürlich auch Kritik dazu. https://t.co/RaPiPN14GD
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
@VeritasLos @DorotheaBaur @skepteis @sonmuda Da die Studie und das Kritikpaper. https://t.co/RaPiPN14GD
@CharlesFLehman There isn't a live scientific debate-- they're one of the most prescribed medicines in America and they clearly work for lots of people. Not everyone benefits from them, but you can easily find tons of people for whom SSRIs were a life chan
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
Nicht wirklich. Die Arbeit von Munkholm et al weist einige methodische Mängel genau dieser Cipriani-Analyse nach.
Das wäre die riesige Metastudie, die man eigentlich hätte verlinken müssen. 🤷🏼♀️ https://t.co/Qp3yK04toJ
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @allyrooney: Cue media hysteria with articles or headlines, reporting this study, implying that 'antidepressants are not grounded in sci…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
@Lauren_Steiner @HowardBlandy34_ @Arbitrarymagi @Inkaino Then go to The Lancet: https://t.co/KW47LrMHdx
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
@SocialistMMA https://t.co/CVLg2pdMdL Serotonin may not be the reason for depression, but SSRIs still work for who-knows-why
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
RT @RVAwonk: And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a…
And the best available evidence — which is pretty extensive — suggests that antidepressants *do* work. (For example, here’s a 2018 meta-analysis of RCT’s that found just that). The new serotonin study doesn’t change this. It didn’t even look at this. htt
@EMPJohnCNewman @BadMedicalTakes https://t.co/uQInmbInjJ More modern studies have been finding that they are effective. The belief that they don’t do anything is mostly rooted in the 90s and early 2000s.
Antidepressants work. This meta analysis review found in a review of “522 trials comprising 116 477 participants. In terms of efficacy, all antidepressants were more effective than placebo” 2/ https://t.co/1twSY53EkQ https://t.co/xaLVLCj56N
@sainsburysban @BettyBlue168 Thanks for being so kind as to tell me how science works, but I'll leave it to the experts if that's ok: https://t.co/3Buog5Jvdo The drugs are designed to treat depression; there's ample evidence that they do. I note no evidenc
RT @allyrooney: Cue media hysteria with articles or headlines, reporting this study, implying that 'antidepressants are not grounded in sci…
@MattWalshBlog Matt, please read over this review/meta-analysis of 522 trials comprising 116,477 participants on antidepressant efficacy https://t.co/jBSrv4nGl3
Please don’t stop taking your SSRIs!
@NasskauLeo @lydlud_locked There's problems with that model but it illustrates my point I think. The question about whether we should use SSRIs boils to down whether there's evidence to support the idea that they improve outcomes. And atm there is https://
@daniel__harley Of course. And the problem with it is subjectivity, plus suppression of adverse results. Marcia Angell produced a good summary in the NYRB some years ago. In anaesthesia, these problems do not exist. There's an objective measure external to
Le evidenze circa l'efficacia e la sicurezza delle terapie sono ormai solide (https://t.co/fKVPqNjqvm). 💊 E allora, perché funzionano? La domanda su COME funzionano i farmaci è diversa da quella che cerca di rispondere SE funzionano. 3/n
@hayek0101 This meta-analysis controlled exactly for that by collecting the largest ever amount of unpublished data and by performing statistical analysis on top, crucially only on unpublished studies. They also collected data on ongoing studies, not yet d
@ClarkeMicah Surely while carrying out the research for your article you read at least some of the innumerable studies on the efficacy of SSRIs and other anti-depressants in treating depressive disorders? If not, see below. https://t.co/NpX9vDya9t
@JCBoyce85 @nahbois @KodiMamabear22 @JackPosobiec Yes you can when controlled clinical studies demonstrate efficacy of SSRIs compared to placebos. https://t.co/vpTmcyfR2O
@iskander They are better than placebo and will benefit some subset of the population of those who suffer from depression https://t.co/9nutudJm7q
@XPRMNT_ https://t.co/gboWlCwUy5 こういう?専門じゃないんですよく分からんですが。
@Lostwanderfound @semiliterate @GrumpyTheology and acceptability in head-to-head trials. These results should serve evidence-based practice and inform patients, physicians, guideline developers, and policy makers on the relative merits of the different ant
RT @garwboy: This isn't to say SSRI's ARE placebos, as has been insisted a lot in the last few days, because they're not. There's buckets o…
This isn't to say SSRI's ARE placebos, as has been insisted a lot in the last few days, because they're not. There's buckets of evidence which show they have notable, tangible effects and benefits. https://t.co/oY4amGBiLB /20
Media getting in a flat spin re anti-depressants. Also lots of n=1 chat about how they weren’t effective for their depression. Efficacy has been demonstrated. Monoamine theory is just that - a possible explanation. Preferred treatment modality also key htt
@kevsheldrake @lynnbixenspan Cipriani et al 2018: https://t.co/NrN82TeonZ
RT @allyrooney: Cue media hysteria with articles or headlines, reporting this study, implying that 'antidepressants are not grounded in sci…
RT @allyrooney: Cue media hysteria with articles or headlines, reporting this study, implying that 'antidepressants are not grounded in sci…