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The bridge helix coordinates movements of modules in RNA polymerase

Overview of attention for article published in BMC Biology, November 2010
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Title
The bridge helix coordinates movements of modules in RNA polymerase
Published in
BMC Biology, November 2010
DOI 10.1186/1741-7007-8-141
Pubmed ID
Authors

Pyae P Hein, Robert Landick

Abstract

The RNA polymerase 'bridge helix' is a metastable α-helix that spans the leading edge of the enzyme active-site cleft. A new study published in BMC Biology reveals surprising tolerance to helix-disrupting changes in a region previously thought crucial for translocation, and suggests roles for two hinge-like segments of the bridge helix in coordinating modules that move during the nucleotide-addition cycle.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Finland 1 2%
France 1 2%
Brazil 1 2%
Unknown 61 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 19%
Student > Master 6 9%
Researcher 6 9%
Professor 6 9%
Other 5 8%
Other 11 17%
Unknown 18 28%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 20 31%
Agricultural and Biological Sciences 20 31%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Immunology and Microbiology 1 2%
Medicine and Dentistry 1 2%
Other 2 3%
Unknown 18 28%