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Antivenom therapy: efficacy of premedication for the prevention of adverse reactions

Overview of attention for article published in Journal of Venomous Animals and Toxins including Tropical Diseases, February 2018
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  • Good Attention Score compared to outputs of the same age (65th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

Mentioned by

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7 X users
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2 Facebook pages

Citations

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29 Dimensions

Readers on

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66 Mendeley
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Title
Antivenom therapy: efficacy of premedication for the prevention of adverse reactions
Published in
Journal of Venomous Animals and Toxins including Tropical Diseases, February 2018
DOI 10.1186/s40409-018-0144-0
Pubmed ID
Authors

Victor Morais

Abstract

Antivenoms or antitoxins have been effectively used for more than a century. During this time, these products have always proven to be highly effective in the treatment of infections and envenomations. However, antivenoms did not exhibit good safety results in their initial applications. After many improvements, antivenoms have substantially better safety profiles but still have some side effects. Due to the occurrence of adverse reactions, the practice of using premedication with the intent to decrease side effects has become accepted or mandatory in many countries. The drugs used for premedication belong to the histamine H1 antagonist, glucocorticoid and catecholamine groups. Currently, this practice is being questioned due to low or controversial efficacies in clinical assays. In this article, we discuss the causes of adverse reactions, the mechanisms of drugs that block the undesired effects and the results obtained in clinical trials. Although these three families of drugs could have positive effects on reducing adverse reactions, only adrenaline has demonstrated positive results in clinical assays.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 66 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 12%
Student > Bachelor 8 12%
Student > Master 7 11%
Student > Ph. D. Student 7 11%
Other 4 6%
Other 14 21%
Unknown 18 27%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 9 14%
Biochemistry, Genetics and Molecular Biology 9 14%
Medicine and Dentistry 8 12%
Agricultural and Biological Sciences 6 9%
Veterinary Science and Veterinary Medicine 3 5%
Other 9 14%
Unknown 22 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 March 2018.
All research outputs
#7,223,028
of 25,591,967 outputs
Outputs from Journal of Venomous Animals and Toxins including Tropical Diseases
#135
of 544 outputs
Outputs of similar age
#117,641
of 344,580 outputs
Outputs of similar age from Journal of Venomous Animals and Toxins including Tropical Diseases
#5
of 10 outputs
Altmetric has tracked 25,591,967 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 544 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,580 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.