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Antivenom therapy: efficacy of premedication for the prevention of adverse reactions

Overview of attention for article published in Journal of Venomous Animals and Toxins including Tropical Diseases, February 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#45 of 399)
  • Good Attention Score compared to outputs of the same age (73rd percentile)

Mentioned by

twitter
10 tweeters
facebook
2 Facebook pages

Citations

dimensions_citation
11 Dimensions

Readers on

mendeley
29 Mendeley
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Title
Antivenom therapy: efficacy of premedication for the prevention of adverse reactions
Published in
Journal of Venomous Animals and Toxins including Tropical Diseases, February 2018
DOI 10.1186/s40409-018-0144-0
Pubmed ID
Authors

Victor Morais

Abstract

Antivenoms or antitoxins have been effectively used for more than a century. During this time, these products have always proven to be highly effective in the treatment of infections and envenomations. However, antivenoms did not exhibit good safety results in their initial applications. After many improvements, antivenoms have substantially better safety profiles but still have some side effects. Due to the occurrence of adverse reactions, the practice of using premedication with the intent to decrease side effects has become accepted or mandatory in many countries. The drugs used for premedication belong to the histamine H1 antagonist, glucocorticoid and catecholamine groups. Currently, this practice is being questioned due to low or controversial efficacies in clinical assays. In this article, we discuss the causes of adverse reactions, the mechanisms of drugs that block the undesired effects and the results obtained in clinical trials. Although these three families of drugs could have positive effects on reducing adverse reactions, only adrenaline has demonstrated positive results in clinical assays.

Twitter Demographics

The data shown below were collected from the profiles of 10 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 29 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 17%
Student > Bachelor 4 14%
Lecturer 3 10%
Other 3 10%
Student > Ph. D. Student 3 10%
Other 8 28%
Unknown 3 10%
Readers by discipline Count As %
Medicine and Dentistry 6 21%
Biochemistry, Genetics and Molecular Biology 5 17%
Pharmacology, Toxicology and Pharmaceutical Science 4 14%
Veterinary Science and Veterinary Medicine 2 7%
Agricultural and Biological Sciences 1 3%
Other 4 14%
Unknown 7 24%

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 March 2018.
All research outputs
#3,023,572
of 16,110,746 outputs
Outputs from Journal of Venomous Animals and Toxins including Tropical Diseases
#45
of 399 outputs
Outputs of similar age
#73,382
of 279,123 outputs
Outputs of similar age from Journal of Venomous Animals and Toxins including Tropical Diseases
#1
of 1 outputs
Altmetric has tracked 16,110,746 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 399 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,123 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them