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The Frizzled family: receptors for multiple signal transduction pathways

Overview of attention for article published in Genome Biology, June 2004
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

twitter
1 X user
patent
1 patent
wikipedia
6 Wikipedia pages

Citations

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200 Dimensions

Readers on

mendeley
341 Mendeley
citeulike
2 CiteULike
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Title
The Frizzled family: receptors for multiple signal transduction pathways
Published in
Genome Biology, June 2004
DOI 10.1186/gb-2004-5-7-234
Pubmed ID
Authors

Hui-Chuan Huang, Peter S Klein

Abstract

Frizzled genes encode integral membrane proteins that function in multiple signal transduction pathways. They have been identified in diverse animals, from sponges to humans. The family is defined by conserved structural features, including seven hydrophobic domains and a cysteine-rich ligand-binding domain. Frizzled proteins are receptors for secreted Wnt proteins, as well as other ligands, and also play a critical role in the regulation of cell polarity. Frizzled genes are essential for embryonic development, tissue and cell polarity, formation of neural synapses, and the regulation of proliferation, and many other processes in developing and adult organisms; mutations in human frizzled-4 have been linked to familial exudative vitreoretinopathy. It is not yet clear how Frizzleds couple to downstream effectors, and this is a focus of intense study.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 341 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 2 <1%
United States 2 <1%
Germany 1 <1%
Chile 1 <1%
Norway 1 <1%
Italy 1 <1%
Austria 1 <1%
Portugal 1 <1%
Finland 1 <1%
Other 3 <1%
Unknown 327 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 95 28%
Student > Bachelor 57 17%
Researcher 45 13%
Student > Master 34 10%
Student > Doctoral Student 14 4%
Other 44 13%
Unknown 52 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 112 33%
Biochemistry, Genetics and Molecular Biology 99 29%
Medicine and Dentistry 18 5%
Chemistry 12 4%
Neuroscience 10 3%
Other 34 10%
Unknown 56 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2023.
All research outputs
#5,240,498
of 25,374,647 outputs
Outputs from Genome Biology
#2,860
of 4,467 outputs
Outputs of similar age
#10,410
of 62,446 outputs
Outputs of similar age from Genome Biology
#3
of 18 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 62,446 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.