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Intasome architecture and chromatin density modulate retroviral integration into nucleosome

Overview of attention for article published in Retrovirology, February 2015
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  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

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6 X users

Citations

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48 Dimensions

Readers on

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45 Mendeley
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1 CiteULike
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Title
Intasome architecture and chromatin density modulate retroviral integration into nucleosome
Published in
Retrovirology, February 2015
DOI 10.1186/s12977-015-0145-9
Pubmed ID
Authors

Mohamed Salah Benleulmi, Julien Matysiak, Daniel Rodrigo Henriquez, Cédric Vaillant, Paul Lesbats, Christina Calmels, Monica Naughtin, Oscar Leon, Anna Marie Skalka, Marc Ruff, Marc Lavigne, Marie-Line Andreola, Vincent Parissi

Abstract

Retroviral integration depends on the interaction between intasomes, host chromatin and cellular targeting cofactors as LEDGF/p75 or BET proteins. Previous studies indicated that the retroviral integrase, by itself, may play a role in the local integration site selection within nucleosomal target DNA. We focused our study on this local association by analyzing the intrinsic properties of various retroviral intasomes to functionally accommodate different chromatin structures in the lack of other cofactors.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Austria 1 2%
Unknown 44 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 33%
Researcher 8 18%
Student > Master 6 13%
Student > Bachelor 4 9%
Professor > Associate Professor 2 4%
Other 4 9%
Unknown 6 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 40%
Biochemistry, Genetics and Molecular Biology 13 29%
Physics and Astronomy 2 4%
Immunology and Microbiology 2 4%
Chemistry 2 4%
Other 2 4%
Unknown 6 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 April 2015.
All research outputs
#14,387,928
of 25,373,627 outputs
Outputs from Retrovirology
#604
of 1,273 outputs
Outputs of similar age
#175,917
of 361,204 outputs
Outputs of similar age from Retrovirology
#12
of 27 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,273 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 361,204 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.