@hanniepower @stephrstephr @sturalph @womeninmalaria @acmcip Monocytes and neutrophils are the issue. Take them out and hurbc can stay very long in circulation, size isn't really that different between human and mouse, see flow cytometry data in ref 10 and
Again, this was first shown in liver-humanized mice transfused with human RBCs: https://t.co/du7YePBLby
@Halene_lab @FlavellLab @LShanlab @Dr_YuanbinSong @Rana_Gbyli @YaleHematology Or one could just overload the innate immune response with human RBCs and get stable ebgraftment,like we did in 2016 and published in 2018... No idea how you could have missed th
@YaleCancer @Dr_YuanbinSong @HaleneLab @FlavellLab @ScienceMagazine @SmilowCancer @YaleMed @YNHH @Rana_Gbyli @OncoAlert Not sure how you could have missed the original human RBC papers... All mentioned in our paper. Might want to get rid of neutrophils bef