Title |
Myocardial T2 mapping reveals age- and sex-related differences in volunteers
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Published in |
Critical Reviews in Diagnostic Imaging, February 2015
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DOI | 10.1186/s12968-015-0118-0 |
Pubmed ID | |
Authors |
Florian Bönner, Niko Janzarik, Christoph Jacoby, Maximilian Spieker, Bernhard Schnackenburg, Felix Range, Britta Butzbach, Sebastian Haberkorn, Ralf Westenfeld, Mirja Neizel-Wittke, Ulrich Flögel, Malte Kelm |
Abstract |
T2 mapping indicates to be a sensitive method for detection of tissue oedema hidden beyond the detection limits of T2-weighted Cardiovascular Magnetic Resonance (CMR). However, due to variability of baseline T2 values in volunteers, reference values need to be defined. Therefore, the aim of the study was to investigate the effects of age and sex on quantitative T2 mapping with a turbo gradient-spin-echo (GRASE) sequence at 1.5 T. For that reason, we studied sensitivity issues as well as technical and biological effects on GRASE-derived myocardial T2 maps. Furthermore, intra- and interobserver variability were calculated using data from a large volunteer group. |
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