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MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neureceptor status in breast cancer

Overview of attention for article published in Breast Cancer Research, May 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)

Mentioned by

patent
6 patents
wikipedia
4 Wikipedia pages

Citations

dimensions_citation
310 Dimensions

Readers on

mendeley
236 Mendeley
citeulike
4 CiteULike
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Title
MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neureceptor status in breast cancer
Published in
Breast Cancer Research, May 2009
DOI 10.1186/bcr2257
Pubmed ID
Authors

Aoife J Lowery, Nicola Miller, Amanda Devaney, Roisin E McNeill, Pamela A Davoren, Christophe Lemetre, Vladimir Benes, Sabine Schmidt, Jonathon Blake, Graham Ball, Michael J Kerin

Abstract

Breast cancer is a heterogeneous disease encompassing a number of phenotypically diverse tumours. Expression levels of the oestrogen, progesterone and HER2/neu receptors which characterize clinically distinct breast tumours have been shown to change during disease progression and in response to systemic therapies. Mi(cro)RNAs play critical roles in diverse biological processes and are aberrantly expressed in several human neoplasms including breast cancer, where they function as regulators of tumour behaviour and progression. The aims of this study were to identify miRNA signatures that accurately predict the oestrogen receptor (ER), progesterone receptor (PR) and HER2/neu receptor status of breast cancer patients to provide insight into the regulation of breast cancer phenotypes and progression.

Mendeley readers

The data shown below were compiled from readership statistics for 236 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 1%
Brazil 3 1%
Iran, Islamic Republic of 2 <1%
Spain 2 <1%
United Kingdom 1 <1%
Latvia 1 <1%
Sweden 1 <1%
Australia 1 <1%
Canada 1 <1%
Other 6 3%
Unknown 215 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 62 26%
Student > Ph. D. Student 43 18%
Student > Master 29 12%
Student > Bachelor 24 10%
Student > Doctoral Student 18 8%
Other 46 19%
Unknown 14 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 101 43%
Medicine and Dentistry 57 24%
Biochemistry, Genetics and Molecular Biology 39 17%
Computer Science 11 5%
Pharmacology, Toxicology and Pharmaceutical Science 3 1%
Other 5 2%
Unknown 20 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 February 2019.
All research outputs
#1,949,644
of 14,780,886 outputs
Outputs from Breast Cancer Research
#303
of 1,587 outputs
Outputs of similar age
#40,871
of 282,989 outputs
Outputs of similar age from Breast Cancer Research
#2
of 2 outputs
Altmetric has tracked 14,780,886 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,587 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.0. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 282,989 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.