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Sphingolipids as Signaling and Regulatory Molecules

Overview of attention for book
Cover of 'Sphingolipids as Signaling and Regulatory Molecules'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 An overview of sphingolipid metabolism: from synthesis to breakdown
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    Chapter 2 Sphingolipid Transport
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    Chapter 3 Sphingolipid Analysis by High Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS)
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    Chapter 4 Ceramide synthases: roles in cell physiology and signaling.
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    Chapter 5 Tales and mysteries of the enigmatic sphingomyelin synthase family.
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    Chapter 6 Ceramide in Stress Response
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    Chapter 7 Animal models for studying the pathophysiology of ceramide.
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    Chapter 8 Ceramide-1-Phosphate in Cell Survival and Inflammatory Signaling
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    Chapter 9 Ceramide-1-Phosphate in Phagocytosis and Calcium Homeostasis
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    Chapter 10 Extracellular and intracellular actions of sphingosine-1-phosphate.
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    Chapter 11 Glucosylceramide in Humans
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    Chapter 12 Gangliosides as Regulators of Cell Membrane Organization and Functions
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    Chapter 13 Cancer treatment strategies targeting sphingolipid metabolism.
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    Chapter 14 Therapeutic Strategies for Diabetes and Complications: A Role for Sphingolipids?
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    Chapter 15 Roles for Sphingolipids in Saccharomyces cerevisiae
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    Chapter 16 Sphingolipid signaling in fungal pathogens.
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    Chapter 17 Sphingolipids in Parasitic Protozoa
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    Chapter 18 Biosynthesis of Sphingolipids in Plants (and Some of Their Functions)
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    Chapter 19 Computational analysis of sphingolipid pathway systems.
Attention for Chapter 4: Ceramide synthases: roles in cell physiology and signaling.
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

wikipedia
1 Wikipedia page

Citations

dimensions_citation
36 Dimensions

Readers on

mendeley
53 Mendeley
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1 CiteULike
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Chapter title
Ceramide synthases: roles in cell physiology and signaling.
Chapter number 4
Book title
Sphingolipids as Signaling and Regulatory Molecules
Published in
Advances in experimental medicine and biology, October 2010
DOI 10.1007/978-1-4419-6741-1_4
Pubmed ID
Book ISBNs
978-1-4419-6740-4, 978-1-4419-6741-1
Authors

Stiban J, Tidhar R, Futerman AH, Johnny Stiban, Rotem Tidhar, Anthony H. Futerman

Abstract

Ceramide synthases (CerS) are integral membrane proteins of the endoplasmic reticulum. Six mammalian CerS have been described, with each utilizing fatty acyl CoAs of relatively defined chain lengths for N-acylation of the sphingoid long chain base. In this chapter, we review the main functional features of the CerS proteins, discuss their fatty acid specificity, kinetics, tissue distribution and mode of inhibition, as well as possible posttranslational modifications. We then address the reason that mammals contain six distinct CerS, whereas most other enzymes in the sphingolipid biosynthetic pathway only occur in one or two isoforms. Finally, we discuss the putative roles of CerS and the ceramide derived from the CerS, in signaling pathways and in development of disease.

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 2 4%
Austria 1 2%
Unknown 50 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 30%
Student > Ph. D. Student 11 21%
Student > Master 7 13%
Student > Bachelor 5 9%
Professor 4 8%
Other 8 15%
Unknown 2 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 49%
Medicine and Dentistry 8 15%
Chemistry 7 13%
Pharmacology, Toxicology and Pharmaceutical Science 3 6%
Biochemistry, Genetics and Molecular Biology 3 6%
Other 4 8%
Unknown 2 4%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2014.
All research outputs
#816,171
of 3,630,565 outputs
Outputs from Advances in experimental medicine and biology
#116
of 970 outputs
Outputs of similar age
#25,504
of 97,978 outputs
Outputs of similar age from Advances in experimental medicine and biology
#4
of 48 outputs
Altmetric has tracked 3,630,565 research outputs across all sources so far. This one has received more attention than most of these and is in the 63rd percentile.
So far Altmetric has tracked 970 research outputs from this source. They receive a mean Attention Score of 2.2. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 97,978 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 48 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.