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Genomic Characterization of Listeria monocytogenes Isolates Associated with Clinical Listeriosis and the Food Production Environment in Ireland

Overview of attention for article published in Genes, March 2018
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (62nd percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

Mentioned by

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6 tweeters

Citations

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30 Dimensions

Readers on

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78 Mendeley
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Title
Genomic Characterization of Listeria monocytogenes Isolates Associated with Clinical Listeriosis and the Food Production Environment in Ireland
Published in
Genes, March 2018
DOI 10.3390/genes9030171
Pubmed ID
Authors

Amber Hilliard, Dara Leong, Amy O’Callaghan, Eamonn Culligan, Ciara Morgan, Niall DeLappe, Colin Hill, Kieran Jordan, Martin Cormican, Cormac Gahan

Abstract

Listeria monocytogenes is a major human foodborne pathogen that is prevalent in the natural environment and has a high case fatality rate. Whole genome sequencing (WGS) analysis has emerged as a valuable methodology for the classification ofL. monocytogenesisolates and the identification of virulence islands that may influence infectivity. In this study, WGS was used to provide an insight into 25L. monocytogenesisolates from cases of clinical infection in Ireland between 2013 and 2015. Clinical strains were either lineage I (14 isolates) or lineage II (11 isolates), with 12 clonal complexes (CC) represented, of which CC1 (6) and CC101 (4) were the most common. Single nucleotide polymorphism (SNP) analysis demonstrated that clinical isolates from mother-infant pairs (one isolate from the mother and one from the infant) were highly related (3 SNP differences in each) and also identified close similarities between isolates from otherwise distinct cases (1 SNP difference). Clinical strains were positive for common virulence-associated loci and 13 isolates harbour the LIPI-3 locus. Pulsed-field gel electrophoresis (PFGE) was used to compare strains to a database of 1300 Irish food and food processing environment isolates and determined that 64% of clinical pulsotypes were previously encountered in the food or food processing environment. Five of the matching food and food processing environment isolates were sequenced and results demonstrated a correlation between pulsotype and genotype. Overall, the work provides insights into the nature ofL. monocytogenesstrains currently causing clinical disease in Ireland and indicates that similar isolates can be found in the food or food processing environment.

Twitter Demographics

The data shown below were collected from the profiles of 6 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 78 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 17%
Student > Ph. D. Student 12 15%
Student > Bachelor 9 12%
Student > Master 6 8%
Professor > Associate Professor 5 6%
Other 10 13%
Unknown 23 29%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 21%
Biochemistry, Genetics and Molecular Biology 11 14%
Immunology and Microbiology 8 10%
Veterinary Science and Veterinary Medicine 4 5%
Environmental Science 4 5%
Other 9 12%
Unknown 26 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 May 2018.
All research outputs
#3,750,908
of 12,884,059 outputs
Outputs from Genes
#343
of 1,336 outputs
Outputs of similar age
#101,166
of 270,722 outputs
Outputs of similar age from Genes
#42
of 132 outputs
Altmetric has tracked 12,884,059 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 1,336 research outputs from this source. They receive a mean Attention Score of 4.4. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 270,722 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.
We're also able to compare this research output to 132 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.