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IQGAP1 and IQGAP2 are Reciprocally Altered in Hepatocellular Carcinoma

Overview of attention for article published in BMC Gastroenterology, October 2010
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Title
IQGAP1 and IQGAP2 are Reciprocally Altered in Hepatocellular Carcinoma
Published in
BMC Gastroenterology, October 2010
DOI 10.1186/1471-230x-10-125
Pubmed ID
Authors

Colin D White, Hema Khurana, Dmitri V Gnatenko, Zhigang Li, Robert D Odze, David B Sacks, Valentina A Schmidt

Abstract

IQGAP1 and IQGAP2 are homologous members of the IQGAP family of scaffold proteins. Accumulating evidence implicates IQGAPs in tumorigenesis. We recently reported that IQGAP2 deficiency leads to the development of hepatocellular carcinoma (HCC) in mice. In the current study we extend these findings, and investigate IQGAP1 and IQGAP2 expression in human HCC.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Australia 1 2%
Unknown 44 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 24%
Student > Master 9 20%
Researcher 7 15%
Student > Bachelor 7 15%
Student > Doctoral Student 2 4%
Other 5 11%
Unknown 5 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 33%
Biochemistry, Genetics and Molecular Biology 14 30%
Medicine and Dentistry 8 17%
Nursing and Health Professions 1 2%
Immunology and Microbiology 1 2%
Other 1 2%
Unknown 6 13%