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Solid Organ Transplantation in Patients With Preexisting Malignancies in Remission

Overview of attention for article published in Transplantation, July 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

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Citations

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34 Dimensions

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Title
Solid Organ Transplantation in Patients With Preexisting Malignancies in Remission
Published in
Transplantation, July 2018
DOI 10.1097/tp.0000000000002178
Pubmed ID
Authors

Sergio A. Acuna, Rinku Sutradhar, S. Joseph Kim, Nancy N. Baxter

Abstract

Solid organ transplant recipients (SOTR) with pretransplant malignancies (PTM) have worse overall survival (OS) compared to recipients without history of malignancy. However, it is unknown whether the increased risk of mortality is due to recurrent cancer-related deaths. All SOTR in Ontario between 1991 and 2010 were identified and matched 1:2 to recipients without PTM using a propensity score. OS was compared using the Kaplan-Meier estimator and Cox proportional hazard models. For cancer-specific mortality and cancer recurrence, cause-specific hazard models were used and the cumulative incidence was plotted. Recipients with PTM had a worse OS compared to recipients without PTM (median OS: 10.3 versus 13.4 years). Recipients with PTM were not only at increased risk of cancer-specific mortality (CSHR:1.85 [95%CI: 1.20, 2.86]) but also at increased risk of noncancer death (CSHR:1.29 [95%CI: 1.08, 1.54]). Compared to recipients without PTM, recipients with high-risk PTM had higher all-cause mortality (HR:1.81 [95%CI: 1.47, 2.23]). Recipients with low-risk PTM were not at increased risk (HR:1.06 [95%CI: 0.86, 1.31]). Recipients with PTM are at increased risk of all-cause mortality compared to recipients without PTM. This increased risk was noted for both cancer-specific and noncancer mortality. However, only those with high-risk PTM had worse outcomes.

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X Demographics

The data shown below were collected from the profiles of 19 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Other 6 26%
Researcher 4 17%
Professor 2 9%
Unspecified 2 9%
Student > Ph. D. Student 2 9%
Other 4 17%
Unknown 3 13%
Readers by discipline Count As %
Medicine and Dentistry 13 57%
Unspecified 2 9%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Arts and Humanities 1 4%
Unknown 6 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 June 2019.
All research outputs
#3,445,042
of 24,040,389 outputs
Outputs from Transplantation
#612
of 7,390 outputs
Outputs of similar age
#67,948
of 331,754 outputs
Outputs of similar age from Transplantation
#13
of 101 outputs
Altmetric has tracked 24,040,389 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,390 research outputs from this source. They receive a mean Attention Score of 5.0. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,754 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 101 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.