Title |
Overexpression of cathepsin f, matrix metalloproteinases 11 and 12 in cervical cancer
|
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Published in |
BMC Cancer, June 2005
|
DOI | 10.1186/1471-2407-5-68 |
Pubmed ID | |
Authors |
Guelaguetza Vazquez-Ortiz, Patricia Pina-Sanchez, Karla Vazquez, Alfonso Duenas, Lucia Taja, Patricia Mendoza, José A Garcia, Mauricio Salcedo |
Abstract |
Cervical carcinoma (CC) is one of the most common cancers among women worldwide and the first cause of death among the Mexican female population. CC progression shows a continuum of neoplastic transitions until invasion. Matrix metalloproteinases (MMPs) and cathepsins play a central role on the enhancement of tumor-induced angiogenesis, cell migration, proliferation, apoptosis and connective tissue degradation. MMPs -2 and -9 expression has been widely studied in cervical cancer. Nevertheless, no other metalloproteinases or cathepsins have been yet related with the progression and/or invasion of this type of cancer. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Slovenia | 1 | 1% |
Mexico | 1 | 1% |
Argentina | 1 | 1% |
United States | 1 | 1% |
Poland | 1 | 1% |
Unknown | 63 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 13 | 19% |
Student > Master | 10 | 15% |
Student > Ph. D. Student | 9 | 13% |
Student > Doctoral Student | 6 | 9% |
Professor | 4 | 6% |
Other | 14 | 21% |
Unknown | 12 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 19 | 28% |
Agricultural and Biological Sciences | 16 | 24% |
Medicine and Dentistry | 14 | 21% |
Environmental Science | 1 | 1% |
Immunology and Microbiology | 1 | 1% |
Other | 3 | 4% |
Unknown | 14 | 21% |