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The clinical relevance of the metabolism of prostate cancer; zinc and tumor suppression: connecting the dots

Overview of attention for article published in Molecular Cancer, May 2006
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  • Good Attention Score compared to outputs of the same age (66th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
1 X user
wikipedia
1 Wikipedia page

Citations

dimensions_citation
321 Dimensions

Readers on

mendeley
236 Mendeley
citeulike
1 CiteULike
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Title
The clinical relevance of the metabolism of prostate cancer; zinc and tumor suppression: connecting the dots
Published in
Molecular Cancer, May 2006
DOI 10.1186/1476-4598-5-17
Pubmed ID
Authors

Leslie C Costello, Renty B Franklin

Abstract

The genetic and molecular mechanisms responsible for and associated specifically with the development and progression of malignant prostate cells are largely unidentified. In addition, despite its implication in virtually all malignant cells, the role of altered cellular metabolism as an essential factor in prostate malignancy has been largely ignored. Moreover, the intermediary metabolism of normal prostate as well as malignant prostate cells is among the least studied and most poorly understood of all mammalian cells. Some important factors, especially the role of zinc, have been identified and implicated in the development and progression of prostate malignancy. In this review, we provide a current and updated integrated assessment of the relationships of intermediary metabolism in normal prostate and in prostate cancer. The experimental and clinical evidence that leads to the formulation of concepts of normal and malignant prostate metabolism is presented. The evidence for a concept of zinc as a tumor suppressor agent and Zip1 zinc transporter as a tumor-suppressor gene is described.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 236 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
India 2 <1%
United Kingdom 2 <1%
Canada 1 <1%
Netherlands 1 <1%
Thailand 1 <1%
Singapore 1 <1%
Spain 1 <1%
Lebanon 1 <1%
Other 0 0%
Unknown 224 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 51 22%
Researcher 34 14%
Student > Bachelor 33 14%
Student > Master 32 14%
Professor > Associate Professor 13 6%
Other 43 18%
Unknown 30 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 50 21%
Medicine and Dentistry 42 18%
Biochemistry, Genetics and Molecular Biology 38 16%
Chemistry 24 10%
Engineering 9 4%
Other 29 12%
Unknown 44 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 June 2021.
All research outputs
#7,960,693
of 25,374,917 outputs
Outputs from Molecular Cancer
#634
of 1,918 outputs
Outputs of similar age
#27,769
of 84,767 outputs
Outputs of similar age from Molecular Cancer
#4
of 8 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 1,918 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 84,767 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.