Chapter 1 The Genomic Characteristics and Origin of Chromothripsis

Chapter 2 Clinical Consequences of Chromothripsis and Other Catastrophic Cellular Events

Chapter 3 Potential Role of Chromothripsis in the Genesis of Complex Chromosomal Rearrangements in Human Gametes and Preimplantation Embryo

Chapter 4 Chromothripsis and the Macroevolution Theory

Chapter 5 Analysis of Chromothripsis by Combined FISH and Microarray Analysis

Chapter 6 Chromothripsis Detectable in Small Supernumerary Marker Chromosomes (sSMC) Using Fluorescence In Situ Hybridization (FISH)

Chapter 7 Identification of Chromothripsis in Biopsy Using SNP-Based Microarray

Chapter 8 Detection of Chromothripsis in Plants

Chapter 9 RNA-Seq Analysis to Detect Abnormal Fusion Transcripts Linked to Chromothripsis

Chapter 10 Experimental Determination of Checkpoint Adaptation by Mitotic Shake-Off and Microscopy

Chapter 11 A Role for Retrotransposons in Chromothripsis

Chapter 12 Generation of Micronuclei and Detection of Chromosome Pulverization

Chapter 13 Detection of Impaired DNA Replication and Repair in Micronuclei as Indicators of Genomic Instability and Chromothripsis

Chapter 14 Study of Telomere Dysfunction in TP53 Mutant LoVo Cell Lines as a Model for Genomic Instability

Chapter 15 Genes, Proteins, and Biological Pathways Preventing Chromothripsis

Chapter 16 Expression of Genes Associated with Telomere Homeostasis in TP53 Mutant LoVo Cell Lines as a Model for Genomic Instability

Chapter 17 Chromothripsis Detection and Characterization Using the CTLPScanner Web Server

Chapter 18 ChromothripsisDB: A Curated Database for the Documentation, Visualization, and Mining of Chromothripsis Data

Chapter 19 Time-Lapse Imaging for the Detection of Chromosomal Abnormalities in Primate Preimplantation Embryos

Chapter 20 Correlative Live Imaging and Immunofluorescence for Analysis of Chromosome Segregation in Mouse Preimplantation Embryos

Chapter 21 Experimental Induction of Genome Chaos

Chapter 22 Looking for Broken TAD Boundaries and Changes on DNA Interactions: Clinical Guide to 3D Chromatin Change Analysis in Complex Chromosomal Rearrangements and Chromothripsis