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Efficacy and safety of intravenous iron sucrose in treating adults with iron deficiency anemia

Overview of attention for article published in Revista Brasileira de Hematologia e Hemoterapia, January 2011
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About this Attention Score

  • Among the highest-scoring outputs from this source (#18 of 217)
  • Above-average Attention Score compared to outputs of the same age (62nd percentile)

Mentioned by

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2 patents

Citations

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8 Dimensions

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40 Mendeley
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Title
Efficacy and safety of intravenous iron sucrose in treating adults with iron deficiency anemia
Published in
Revista Brasileira de Hematologia e Hemoterapia, January 2011
DOI 10.5581/1516-8484.20110119
Pubmed ID
Authors

Rodolfo Delfini Cançado, Pedro Otavio Novis de Figueiredo, Maria Cristina Albe Olivato, Carlos Sérgio Chiattone

Abstract

Iron deficiency is the most common disorder in the world, affecting approximately 25% of the world`s population and the most common cause of anemia. To evaluate the efficacy and safety of intravenous iron sucrose (IS) in the treatment of adults with iron deficiency anemia Eighty-six adult patients with iron deficiency anemia, who had intolerance or showed no effect with oral iron therapy, received a weekly dose of 200 mg of intravenous iron sucrose until the hemoglobin level was corrected or until receiving the total dose of intravenous iron calculated for each patient The mean hemoglobin and serum ferritin levels were 8.54 g/dL and 7.63 ng/mL (pre-treatment) and 12.1 g/dL and 99.0 ng/mL (post-treatment) (p-value < 0.0001), respectively. The average increases in hemoglobin levels were 3.29 g/dL for women and 4.58 g/dL for men; 94% of male and 84% of female patients responded (hemoglobin increased by at least 2 g/dL) to intravenous iron therapy. Correction of anemia was obtained in 47 of 69 (68.1%) female patients and in 12 of 17 male (70.6%) patients. A total of 515 intravenous infusions of iron sucrose were administered and iron sucrose was generally well tolerated with no moderate or serious adverse drug reactions recorded by the investigators. Our data confirm that the use of intravenous iron sucrose is a safe and effective option in the treatment of adult patients with iron deficiency anemia who lack satisfactory response to oral iron therapy. Intravenous iron sucrose is well tolerated and with a clinically manageable safety profile when using appropriate dosing and monitoring. The availability of intravenous iron sucrose would potentially improve compliance and thereby reduce morbidities from iron deficiency.

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 40 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 20%
Student > Postgraduate 6 15%
Student > Doctoral Student 5 13%
Student > Master 5 13%
Researcher 5 13%
Other 1 3%
Unknown 10 25%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 13 33%
Medicine and Dentistry 10 25%
Nursing and Health Professions 2 5%
Biochemistry, Genetics and Molecular Biology 1 3%
Agricultural and Biological Sciences 1 3%
Other 1 3%
Unknown 12 30%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 November 2017.
All research outputs
#3,479,215
of 12,167,359 outputs
Outputs from Revista Brasileira de Hematologia e Hemoterapia
#18
of 217 outputs
Outputs of similar age
#98,185
of 265,502 outputs
Outputs of similar age from Revista Brasileira de Hematologia e Hemoterapia
#1
of 1 outputs
Altmetric has tracked 12,167,359 research outputs across all sources so far. This one is in the 49th percentile – i.e., 49% of other outputs scored the same or lower than it.
So far Altmetric has tracked 217 research outputs from this source. They receive a mean Attention Score of 3.5. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 265,502 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them