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Glycosylation Engineering of Biopharmaceuticals

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Cover of 'Glycosylation Engineering of Biopharmaceuticals'

Table of Contents

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    Book Overview
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    Chapter 1 Engineering of Therapeutic and Diagnostic O -Glycans on Recombinant Mucin-Type Immunoglobulin Fusion Proteins Expressed in CHO Cells
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    Chapter 2 Engineering a Human-Like Glycosylation to Produce Therapeutic Glycoproteins Based on 6-Linked Sialylation in CHO Cells
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    Chapter 3 Glycoengineered Pichia -Based Expression of Monoclonal Antibodies
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    Chapter 4 N-Glycosylation Humanization for Production of Therapeutic Recombinant Glycoproteins in Saccharomyces cerevisiae
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    Chapter 5 Engineering the baculovirus genome to produce galactosylated antibodies in lepidopteran cells.
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    Chapter 6 NanoLC Chips MS/MS for the Characterization of N -Glycopeptides Generated from Trypsin Digestion of a Monoclonal Antibody
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    Chapter 7 Cetuximab Fab and Fc N-Glycan Fast Characterization Using IdeS Digestion and Liquid Chromatography Coupled to Electrospray Ionization Mass Spectrometry
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    Chapter 8 Therapeutic Antibody Glycosylation Analysis: A Contract Research Organization Perspective in the Frame of Batch Release or Comparability Support
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    Chapter 9 Mass Spectrometric Analysis of O -Linked Oligosaccharides from Various Recombinant Expression Systems
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    Chapter 10 Assessing Fc Glycan Heterogeneity of Therapeutic Recombinant Monoclonal Antibodies Using NP-HPLC
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    Chapter 11 Application of Capillary Electrophoresis in Glycoprotein Analysis
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    Chapter 12 Characterization of Glycoprotein Biopharmaceutical Products by Caliper LC90 CE-SDS Gel Technology
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    Chapter 13 Hydrophobic Interaction Chromatography to Analyze Glycoproteins
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    Chapter 14 Lectin Glycoprofiling of Recombinant Therapeutic Interleukin-7
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    Chapter 15 Analysis of Monoclonal Antibodies by Sedimentation Velocity Analytical Ultracentrifugation
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    Chapter 16 Noncovalent Mass Spectrometry for the Characterization of Antibody/Antigen Complexes
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    Chapter 17 Conformational Analysis of Recombinant Monoclonal Antibodies with Hydrogen/Deuterium Exchange Mass Spectrometry
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    Chapter 18 Epitope Mapping of Antibodies by Mass Spectroscopy: A Case Study
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    Chapter 19 Evaluation of Antibody-Dependent Cell Cytotoxicity Using Lactate Dehydrogenase (LDH) Measurement
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    Chapter 20 Evaluation of Complement-Dependent Cytotoxicity Using ATP Measurement and C1q/C4b Binding
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    Chapter 21 Capture of the Human IgG1 Antibodies by Protein A for the Kinetic Study of h-IgG/FcγR Interaction Using SPR-Based Biosensor Technology
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    Chapter 22 Mass Spectrometry Protocol for the Absolute Quantification of a Monoclonal Antibody in Serum with Immunopurification
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Title
Glycosylation Engineering of Biopharmaceuticals
Published by
Humana Press, Totowa, NJ, March 2013
DOI 10.1007/978-1-62703-327-5
ISBNs
978-1-62703-326-8, 978-1-62703-327-5
Editors

Alain Beck

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 181 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Hungary 1 <1%
Switzerland 1 <1%
France 1 <1%
Belgium 1 <1%
China 1 <1%
United States 1 <1%
Algeria 1 <1%
Unknown 174 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 53 29%
Researcher 52 29%
Other 23 13%
Student > Master 19 10%
Student > Bachelor 13 7%
Other 15 8%
Unknown 6 3%
Readers by discipline Count As %
Agricultural and Biological Sciences 81 45%
Biochemistry, Genetics and Molecular Biology 36 20%
Chemistry 23 13%
Pharmacology, Toxicology and Pharmaceutical Science 10 6%
Engineering 7 4%
Other 15 8%
Unknown 9 5%