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Regulation of the ITGA2 gene by epigenetic mechanisms in prostate cancer

Overview of attention for article published in The Prostate, February 2015
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2 tweeters

Citations

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Readers on

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12 Mendeley
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Title
Regulation of the ITGA2 gene by epigenetic mechanisms in prostate cancer
Published in
The Prostate, February 2015
DOI 10.1002/pros.22954
Pubmed ID
Authors

Suyin Paulynn Chin, James R. Marthick, Alison C. West, Annabel K. Short, Jyoti Chuckowree, Andrea M. Polanowski, Russell J. Thomson, Adele F. Holloway, Joanne L. Dickinson

Abstract

Integrin alpha2 beta1 (α2 β1 ) plays an integral role in tumour cell invasion, metastasis and angiogenesis, and altered expression of the receptor has been linked to tumour prognosis in several solid tumours. However, the relationship is complex, with both increased and decreased expression associated with different stages of tumour metastases in several tumour types. The ITGA2 gene, which codes for the α2 subunit, was examined to investigate whether a large CpG island associated with its promoter region is involved in the differential expression of ITGA2 observed in prostate cancer.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 8%
Unknown 11 92%

Demographic breakdown

Readers by professional status Count As %
Unspecified 3 25%
Student > Bachelor 2 17%
Researcher 2 17%
Student > Postgraduate 1 8%
Student > Ph. D. Student 1 8%
Other 3 25%
Readers by discipline Count As %
Medicine and Dentistry 4 33%
Unspecified 3 25%
Mathematics 2 17%
Agricultural and Biological Sciences 1 8%
Economics, Econometrics and Finance 1 8%
Other 1 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 February 2015.
All research outputs
#9,738,684
of 12,183,238 outputs
Outputs from The Prostate
#1,524
of 1,795 outputs
Outputs of similar age
#190,281
of 276,598 outputs
Outputs of similar age from The Prostate
#37
of 57 outputs
Altmetric has tracked 12,183,238 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,795 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,598 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.