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Implications of a RAD54L polymorphism (2290C/T) in human meningiomas as a risk factor and/or a genetic marker

Overview of attention for article published in BMC Cancer, March 2003
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Title
Implications of a RAD54L polymorphism (2290C/T) in human meningiomas as a risk factor and/or a genetic marker
Published in
BMC Cancer, March 2003
DOI 10.1186/1471-2407-3-6
Pubmed ID
Authors

Paola E Leone, Marta Mendiola, Javier Alonso, César Paz-y-Miño, Angel Pestaña

Abstract

RAD54L (OMIM 603615, Locus Link 8438) has been proposed as a candidate oncosupressor in tumours bearing a non-random deletion of 1p32, such as breast or colon carcinomas, lymphomas and meningiomas. In a search for RAD54L mutations in 29 menigiomas with allelic deletions in 1p, the only genetic change observed was a silent C/T transition at nucleotide 2290 in exon 18. In this communication the possible association of the 2290C/T polymorphism with the risk of meningiomas was examined. In addition, the usefulness of this polymorphism as a genetic marker within the meningioma consensus deletion region in 1p32 was also verified. The present study comprises 287 blood control samples and 70 meningiomas from Spain and Ecuador. Matched blood samples were only available from Spanish patients.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 21%
Researcher 5 21%
Student > Ph. D. Student 4 17%
Professor > Associate Professor 2 8%
Unspecified 1 4%
Other 2 8%
Unknown 5 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 29%
Biochemistry, Genetics and Molecular Biology 6 25%
Medicine and Dentistry 3 13%
Business, Management and Accounting 1 4%
Unspecified 1 4%
Other 1 4%
Unknown 5 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 December 2007.
All research outputs
#7,454,298
of 22,789,076 outputs
Outputs from BMC Cancer
#2,059
of 8,294 outputs
Outputs of similar age
#16,841
of 49,183 outputs
Outputs of similar age from BMC Cancer
#1
of 2 outputs
Altmetric has tracked 22,789,076 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,294 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 49,183 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them