Chapter 1 The Key Features of RNA Silencing

Chapter 2 Selected Strategies for the Delivery of siRNA In Vitro and In Vivo

Chapter 3 RNAi Suppression and Its Application

Chapter 4 Strategies to Prevent siRNA-Triggered Cellular Toxicity

Chapter 5 RNAi in Malignant Brain Tumors: Relevance to Molecular and Translational Research

Chapter 6 Silencing Huntington’s Disease Gene with RNAi

Chapter 7 Application of Dicer-Substrate siRNA in Pain Research

Chapter 8 RNAi Treatment of HIV-1 Infection

Chapter 9 Application of RNA Interference to Treat Conditions Associated with Dysregulation of Transient Receptor Potential Vanilloid 1 Channel

Chapter 10 Harnessing RNAi-Based Functional Genomics to Unravel the Molecular Complexity Underlying Skin Pigment Variation

Chapter 11 mRNA Structure and its Effects on Posttranscriptional Gene Silencing

Chapter 12 Antisense RNA-Mediated Regulation of the p53 Tumor Suppressor

Chapter 13 Antisense Oligonucleotides: Insights from Preclinical Studies and Clinical Trials

Chapter 14 What can the New Hammerhead Ribozyme Structures Teach us About Design?

Chapter 15 microRNA Biogenesis and its Impact on RNA Interference

Chapter 16 MicroRNAs in Epithelial Antimicrobial Immunity

Chapter 17 Emerging Roles of Long Noncoding RNAs in Gene Expression and Intracellular Organization

Chapter 18 Noncoding RNAs as Therapeutic Targets

Chapter 19 Noncoding RNAs at H19 / IGF2 Locus: Role in Imprinting, Gene Expression, and Associated Pathologies