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Overview of attention for article published in Genome Biology (Online Edition), January 2007
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Title
Published in
Genome Biology (Online Edition), January 2007
DOI 10.1186/gb-2007-8-2-206
Pubmed ID
Authors

Yoko Shiraishi-Yamaguchi, Teiichi Furuichi

Abstract

The Homer family of adaptor proteins consists of three members in mammals, and homologs are also known in other animals but not elsewhere. They are predominantly localized at the postsynaptic density in mammalian neurons and act as adaptor proteins for many postsynaptic density proteins. As a result of alternative splicing each member has several variants, which are classified primarily into the long and short forms. The long Homer forms are constitutively expressed and consist of two major domains: the amino-terminal target-binding domain, which includes an Enabled/vasodilator-stimulated phosphoprotein (Ena/VASP) homology 1 (EVH1) domain, and the carboxy-terminal self-assembly domain containing a coiled-coil structure and leucine zipper motif. Multimers of long Homer proteins, coupled through their carboxy-terminal domains, are thought to form protein clusters with other postsynaptic density proteins, which are bound through the amino-terminal domains. Such Homer-mediated clustering probably regulates or facilitates signal transduction or cross-talk between target proteins. The short Homer forms lack the carboxy-terminal domain; they are expressed in an activity-dependent manner as immediate-early gene products, possibly disrupting Homer clusters by competitive binding to target proteins. Homer proteins are also involved in diverse non-neural physiological functions.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 196 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 2%
France 2 1%
Hungary 2 1%
Germany 2 1%
India 1 <1%
Chile 1 <1%
United Kingdom 1 <1%
Canada 1 <1%
Japan 1 <1%
Other 1 <1%
Unknown 181 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 62 32%
Researcher 43 22%
Student > Bachelor 27 14%
Student > Master 19 10%
Professor 10 5%
Other 24 12%
Unknown 11 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 97 49%
Neuroscience 40 20%
Medicine and Dentistry 16 8%
Biochemistry, Genetics and Molecular Biology 15 8%
Engineering 4 2%
Other 7 4%
Unknown 17 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 October 2019.
All research outputs
#11,552,150
of 14,579,856 outputs
Outputs from Genome Biology (Online Edition)
#3,073
of 3,219 outputs
Outputs of similar age
#192,437
of 283,471 outputs
Outputs of similar age from Genome Biology (Online Edition)
#7
of 7 outputs
Altmetric has tracked 14,579,856 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,219 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 283,471 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one.