Title |
Pollutants in pet dogs: a model for environmental links to breast cancer
|
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Published in |
SpringerPlus, January 2015
|
DOI | 10.1186/s40064-015-0790-4 |
Pubmed ID | |
Authors |
Sabine Sévère, Philippe Marchand, Ingrid Guiffard, Floriane Morio, Anaïs Venisseau, Bruno Veyrand, Bruno Le Bizec, Jean-Philippe Antignac, Jérôme Abadie |
Abstract |
Invasive breast carcinoma is the most common cancer in women as in non-ovariectomised pet dogs, which are already identified as a valuable spontaneous preclinical model for that disease. Geographical and time trends suggest that environmental factors may play an important role in the etiology and pathogenesis of breast cancer. Persistent organic pollutants (POPs) fit perfectly with these trends and are known to interact with hormonal receptors implicated in breast cancer subtyping. The aim of this innovating study was to evaluate the interest of the companion dog model in assessing chemical exposure and breast cancer associations, in order to identify common etiological features with the human disease in a context of comparative oncology. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 56% |
Unknown | 4 | 44% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 78% |
Scientists | 1 | 11% |
Science communicators (journalists, bloggers, editors) | 1 | 11% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
South Africa | 1 | 2% |
Unknown | 55 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 11 | 20% |
Student > Bachelor | 11 | 20% |
Student > Master | 10 | 18% |
Researcher | 3 | 5% |
Student > Doctoral Student | 2 | 4% |
Other | 6 | 11% |
Unknown | 13 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 12 | 21% |
Agricultural and Biological Sciences | 11 | 20% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
Environmental Science | 2 | 4% |
Biochemistry, Genetics and Molecular Biology | 2 | 4% |
Other | 9 | 16% |
Unknown | 17 | 30% |