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A meta-analysis of prospective studies on the role of physical activity and the prevention of Alzheimer’s disease in older adults

Overview of attention for article published in BMC Geriatrics, February 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

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4 news outlets
twitter
9 X users

Citations

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123 Dimensions

Readers on

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251 Mendeley
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Title
A meta-analysis of prospective studies on the role of physical activity and the prevention of Alzheimer’s disease in older adults
Published in
BMC Geriatrics, February 2015
DOI 10.1186/s12877-015-0007-2
Pubmed ID
Authors

Michael W Beckett, Christopher I Ardern, Michael A Rotondi

Abstract

The incidence of Alzheimer's disease is increasing as the global population ages. Given the limited success of pharmaceuticals in preventing this disease, a greater emphasis on non-pharmaceutical approaches is needed. The aim of this study was to quantify the association between Alzheimer's disease and physical activity in older adults over the age of 65 years. A meta-analytic approach was used to determine if physical activity reduced the risk of Alzheimer's disease in individuals 65 years or older. Some evidence indicates that physical activity may improve cognitive function in older adults, while other evidence is inconclusive. The purpose of this study was to examine if prevention of Alzheimer's disease is possible if started at a later age. The precise brain changes that occur with the onset of Alzheimer's disease are not fully known, and therefore may still be influenced by preventative measures even in advancing age. Determining if physical activity can inhibit the onset of the disease at any age may motivate individuals to adopt an "it's never too late" mentality on preventing the onset of this debilitating disease. Longitudinal studies of participants who were 65 years or older at baseline were included. A total of 20,326 participants from nine studies were included in this analysis. The fixed effects risk ratio is estimated as 0.61 (95% CI 0.52-0.73) corresponding to a statistically significant overall reduction in risk of Alzheimer's disease in physically active older adults compared to their non-active counterparts. Physical activity was associated with a reduced risk of Alzheimer's disease in adults over the age of 65 years. Given the limited treatment options, greater emphasis should be paid to primary prevention through physical activity amongst individuals at high-risk of Alzheimer's disease, such as those with strong genetic and family history.

X Demographics

X Demographics

The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 251 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 2 <1%
Greece 1 <1%
Germany 1 <1%
Canada 1 <1%
Unknown 246 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 37 15%
Student > Master 37 15%
Student > Bachelor 37 15%
Researcher 27 11%
Student > Doctoral Student 15 6%
Other 35 14%
Unknown 63 25%
Readers by discipline Count As %
Medicine and Dentistry 46 18%
Psychology 32 13%
Nursing and Health Professions 25 10%
Neuroscience 22 9%
Sports and Recreations 22 9%
Other 31 12%
Unknown 73 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 41. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 March 2022.
All research outputs
#928,536
of 24,092,222 outputs
Outputs from BMC Geriatrics
#135
of 3,326 outputs
Outputs of similar age
#13,572
of 365,597 outputs
Outputs of similar age from BMC Geriatrics
#1
of 28 outputs
Altmetric has tracked 24,092,222 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,326 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.2. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 365,597 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.