Title |
NK cell and DC interactions
|
---|---|
Published in |
Trends in Immunology, January 2004
|
DOI | 10.1016/j.it.2003.10.012 |
Pubmed ID | |
Authors |
Megan A. Cooper, Todd A. Fehniger, Anja Fuchs, Marco Colonna, Michael A. Caligiuri |
Abstract |
Recent interest has focused on interactions between natural killer (NK) cells and dendritic cells (DCs). In vitro and in vivo studies have demonstrated various effects of NK-DC interactions, including activation and cytokine production, maturation of DCs and NK-cell lysis of certain autologous DCs. These interactions are important during an immune response in vivo, however, it remains unclear where in the body NK cells and DCs might interact and whether observed in vitro crosstalk between these cell types happens in vivo. We propose evidence for at least two potential locations of in vivo interactions for human NK cells and DCs, including sites of inflammation and lymph nodes. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 1% |
United Kingdom | 3 | 1% |
France | 2 | <1% |
Brazil | 2 | <1% |
Sweden | 2 | <1% |
Chile | 1 | <1% |
Portugal | 1 | <1% |
India | 1 | <1% |
Colombia | 1 | <1% |
Other | 4 | 2% |
Unknown | 210 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 59 | 26% |
Researcher | 56 | 24% |
Student > Master | 23 | 10% |
Student > Bachelor | 17 | 7% |
Professor > Associate Professor | 17 | 7% |
Other | 43 | 19% |
Unknown | 15 | 7% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 95 | 41% |
Immunology and Microbiology | 40 | 17% |
Medicine and Dentistry | 37 | 16% |
Biochemistry, Genetics and Molecular Biology | 19 | 8% |
Chemistry | 2 | <1% |
Other | 11 | 5% |
Unknown | 26 | 11% |