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New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control

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Cover of 'New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control'

Table of Contents

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    Book Overview
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    Chapter 1 Introductory Remarks
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    Chapter 2 New Trends in Radiopharmaceutical Synthesis Using Positron Emitters: Quality Control
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    Chapter 3 A Muscarinic Receptor Ligand: Review of the Chemistry and Applications
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    Chapter 4 Aspects on the Synthesis and Design of 11 C-Tracers for PET
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    Chapter 5 Special Problems Associated with the Synthesis of High Specific Activity Carbon-11 Labeled Radiotracers
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    Chapter 6 P.E.T. Radiopharmaceuticals Via Reductive Carboxylation
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    Chapter 7 [ 13 N] Labeled Tracers, Synthesis and Applications
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    Chapter 8 CU 1 +Assisted Nucleophilic Exchange Radiohalogenation: Application and Mechanistic Approach
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    Chapter 9 Potential Breast Tumor Imaging Agents: Fluorotamoxifen and Derivatives
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    Chapter 10 Fluorinated Azabicycloesters as Muscarinic Receptor Ligands for Application with PET
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    Chapter 11 Fluorine-18 Ligands for the in Vivo Study of the Beta Adrenergic Receptor in the Heart and Lung
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    Chapter 12 Design and Radiofluorination of Benzamide Dopamine D2 Receptor Ligands
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    Chapter 13 A Synthetic Porphyrin with High Affinity for Lung Cancer Cells and Inflamed Lymphatic Tissue
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    Chapter 14 Gallium and Copper Radiopharmaceutical Chemistry
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    Chapter 15 Radiometallating Antibodies and Autoantigenic Peptides
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    Chapter 16 Biomedical Use of Arsenic Radioisotopes
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    Chapter 17 Improved Extraction Efficiency of Gallium-67 after Irradiation of Zinc-68 with Protons
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    Chapter 18 Chemistry and Concept for an Automated 72 Se/ 72 As Generator
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    Chapter 19 Radiochemistry of Monoclonal Antibody Labeling
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    Chapter 20 The Study on the Formulation of a Tc(V)-99m-DMS Lyophilized Instant Kit for Tumor Scintigraphy
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    Chapter 21 A National Biomedical Tracer Facility (NBTF)
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    Chapter 22 Tantalum-178-Labeled Radiopharmaceutical Synthesis Via the Intermediate Tantalum Pentachloride — A Potential Myocardial Perfusion Agent
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    Chapter 23 Status of Lead and Bismuth for Radioimmunoimaging and Radioimmunotherapy
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    Chapter 24 Use of Organolithium and Organomagnesium Reagents in Radiopharmaceutical Synthesis
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    Chapter 25 Application of Organosilicon Chemistry to the Synthesis of Gamma and Positron Emitting Radiotracers for Use in Nuclear Imaging Studies
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    Chapter 26 The Synthesis of Halogenated Radiopharmaceuticals Using Organomercurials
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    Chapter 27 Synthesis of Radiopharmaceuticals Via Organoboranes
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    Chapter 28 Radioisotope Incorporation Via Aryl and Alkenyl Trialkyltin Intermediates
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    Chapter 29 Robots in the Radiopharmaceutical Laboratory…Will They Replace the Chemist?
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    Chapter 30 The Use of Transducers for Automated Radiopharmaceutical Synthesis Procedures
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    Chapter 31 Facilitating the Design and Operation of Computer-Controlled Radiochemistry Synthesizers with an “Electronic Toolbox”
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    Chapter 32 Knowledge-Based Automated Radiopharmaceutical Manufacturing for Positron Emission Tomography
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    Chapter 33 Robotic Thin Layer Chromatography Instrument for Synthetic Chemistry
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    Chapter 34 Automated Radiochemical Processing for Clinical Pet
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    Chapter 35 Captive Solvent Methods for Fast, Simple Carbon-11 Radioalkylations
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    Chapter 36 Identity, Strength, Purity, Quality, and Safety: Common Goals for New Drugs
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    Chapter 37 Quality Assurance Considerations Related to “In-House” Radiopharmaceutical Preparations Utilizing Positron Emitting Radionuclides
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    Chapter 38 The Role of High Performance Liquid Chromatography in Radiochemical/Radiopharmaceutical Synthesis and Quality Assurance
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    Chapter 39 Experience from a National Quality Assurance System on Radiopharmaceuticals
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    Chapter 40 Radiopharmaceutical Production for PET: Quality Assurance Practice, Experiences and Issues
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    Chapter 41 Post-Column Reactor Determination of Aluminum Concentration in Cyclotron Produced Radiorubidium
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    Chapter 42 Implications of the Food, Drug, and Cosmetic Act on the Quality Assurance of Radiopharmaceuticals used in the United States
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    Chapter 43 Quality Assurance in Radiochemical/Radiopharmaceutical Manufacturing
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    Chapter 44 Regulatory Control of Radiopharmaceutics
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    Chapter 45 Regulatory Control of Radiopharmaceuticals
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    Chapter 46 Development of European Regulations on Radiopharmaceuticals
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    Chapter 47 Regulation of Cyclotron Radiopharmaceutical Production and Distribution: An Agreement State Perspective
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    Chapter 48 New Drug Approval Process for Radiopharmaceuticals
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    Chapter 49 Abbreviated New Drug Applications (ANDAS): Future Trend in Radiopharmaceuticals
Attention for Chapter 26: The Synthesis of Halogenated Radiopharmaceuticals Using Organomercurials
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Chapter title
The Synthesis of Halogenated Radiopharmaceuticals Using Organomercurials
Chapter number 26
Book title
New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control
Published by
Springer, Boston, MA, January 1991
DOI 10.1007/978-1-4899-0626-7_26
Book ISBNs
978-1-4899-0628-1, 978-1-4899-0626-7
Authors

Richard J. Flanagan