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Temperature sensitive influenza A virus genome replication results from low thermal stability of polymerase-cRNA complexes

Overview of attention for article published in Virology Journal, August 2006
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
6 X users
reddit
1 Redditor

Citations

dimensions_citation
58 Dimensions

Readers on

mendeley
66 Mendeley
citeulike
1 CiteULike
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Title
Temperature sensitive influenza A virus genome replication results from low thermal stability of polymerase-cRNA complexes
Published in
Virology Journal, August 2006
DOI 10.1186/1743-422x-3-58
Pubmed ID
Authors

Rosa M Dalton, Anne E Mullin, Maria Joao Amorim, Elizabeth Medcalf, Laurence S Tiley, Paul Digard

Abstract

The RNA-dependent RNA polymerase of Influenza A virus is a determinant of viral pathogenicity and host range that is responsible for transcribing and replicating the negative sense segmented viral genome (vRNA). Transcription produces capped and polyadenylated mRNAs whereas genome replication involves the synthesis of an alternative plus-sense transcript (cRNA) with unmodified termini that is copied back to vRNA. Viral mRNA transcription predominates at early stages of viral infection, while later, negative sense genome replication is favoured. However, the "switch" that regulates the transition from transcription to replication is poorly understood.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 2%
United States 1 2%
Russia 1 2%
Denmark 1 2%
Unknown 62 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 38%
Researcher 12 18%
Professor 4 6%
Student > Bachelor 4 6%
Unspecified 3 5%
Other 10 15%
Unknown 8 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 39%
Biochemistry, Genetics and Molecular Biology 9 14%
Immunology and Microbiology 7 11%
Medicine and Dentistry 6 9%
Unspecified 3 5%
Other 5 8%
Unknown 10 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 April 2023.
All research outputs
#1,971,418
of 25,703,943 outputs
Outputs from Virology Journal
#160
of 3,424 outputs
Outputs of similar age
#3,857
of 92,242 outputs
Outputs of similar age from Virology Journal
#1
of 7 outputs
Altmetric has tracked 25,703,943 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,424 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 19.7. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 92,242 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them