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Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism

Overview of attention for book
Attention for Chapter 329: Genetic Diversity in Mycobacterium tuberculosis.
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  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

Mentioned by

twitter
2 tweeters
facebook
1 Facebook page

Citations

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6 Dimensions

Readers on

mendeley
29 Mendeley
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Chapter title
Genetic Diversity in Mycobacterium tuberculosis.
Chapter number 329
Book title
Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism
Published in
Current topics in microbiology and immunology, May 2013
DOI 10.1007/82_2013_329
Pubmed ID
Book ISBNs
978-3-64-240231-9, 978-3-64-240232-6
Authors

Sebastien Gagneux

Abstract

Recent years have witnessed an increased appreciation of the extent and relevance of strain-to-strain variation in Mycobacterium tuberculosis. This paradigm shift can largely be attributed to an improved understanding of the global population structure of this organism, and to the realisation that the various members of the M. tuberculosis complex (MTBC) harbour more genetic diversity than previously realised. Moreover, many studies using experimental models of infection have demonstrated that MTBC diversity translates into significant differences in immunogenecity and virulence . However, linking these experimental phenotypes to relevant clinical phenotypes has been difficult, and to date, largely unsuccessful. Nevertheless, emerging high-throughput technologies, in particular next-generation sequencing , offer new opportunities, and have already lead to important new insights. Given the complexity of the host-pathogen interaction in tuberculosis, systems approaches will be key to define the role of MTBC diversity in the fight against one of humankind's most important pathogens.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
Canada 1 3%
Unknown 27 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 21%
Researcher 6 21%
Student > Master 5 17%
Professor 3 10%
Other 2 7%
Other 6 21%
Unknown 1 3%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 38%
Biochemistry, Genetics and Molecular Biology 5 17%
Medicine and Dentistry 4 14%
Veterinary Science and Veterinary Medicine 1 3%
Business, Management and Accounting 1 3%
Other 4 14%
Unknown 3 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 April 2014.
All research outputs
#7,675,472
of 12,733,213 outputs
Outputs from Current topics in microbiology and immunology
#282
of 537 outputs
Outputs of similar age
#75,506
of 149,185 outputs
Outputs of similar age from Current topics in microbiology and immunology
#3
of 7 outputs
Altmetric has tracked 12,733,213 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 537 research outputs from this source. They receive a mean Attention Score of 3.2. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 149,185 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.