Chapter title |
Role of calcium in regulating primary sensory neuronal excitability.
|
---|---|
Chapter number | 16 |
Book title |
Sensory Nerves
|
Published in |
Handbook of experimental pharmacology, February 2016
|
DOI | 10.1007/978-3-540-79090-7_16 |
Pubmed ID | |
Book ISBNs |
978-3-54-079089-1, 978-3-54-079090-7
|
Authors |
T.D. Gover, T.H. Moreira, D. Weinreich, Gover TD, Moreira TH, Weinreich D |
Abstract |
The fundamental role of calcium ions (Ca(2+)) in an excitable tissue, the frog heart, was first demonstrated in a series of classical reports by Sydney Ringer in the latter part of the nineteenth century (1882a, b; 1893a, b). Even so, nearly a century elapsed before it was proven that Ca(2+) regulated the excitability of primary sensory neurons. In this chapter we review the sites and mechanisms whereby internal and external Ca(2+) can directly or indirectly alter the excitability of primary sensory neurons: excitability changes being manifested typically by variations in shape of the action potential or the pattern of its discharge. |
Mendeley readers
Geographical breakdown
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Unknown | 13 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Doctoral Student | 2 | 15% |
Student > Bachelor | 2 | 15% |
Student > Master | 2 | 15% |
Researcher | 2 | 15% |
Student > Ph. D. Student | 1 | 8% |
Other | 2 | 15% |
Unknown | 2 | 15% |
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Biochemistry, Genetics and Molecular Biology | 1 | 8% |
Other | 0 | 0% |
Unknown | 2 | 15% |