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Influenza Pathogenesis and Control - Volume I

Overview of attention for book
Cover of 'Influenza Pathogenesis and Control - Volume I'

Table of Contents

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    Book Overview
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    Chapter 383 Mammalian Models for the Study of H7 Virus Pathogenesis and Transmission.
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    Chapter 384 The Hemagglutinin: A Determinant of Pathogenicity.
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    Chapter 385 Influenza Pathobiology and Pathogenesis in Avian Species.
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    Chapter 386 Molecular Determinants of Pathogenicity in the Polymerase Complex
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    Chapter 387 Avian Influenza Virus Transmission to Mammals
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    Chapter 388 Molecular Determinants of Influenza Virus Pathogenesis in Mice.
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    Chapter 389 Enhancement of Influenza Virus Transmission by Gene Reassortment
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    Chapter 390 Transmission in the Guinea Pig Model
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    Chapter 391 Pathogenesis and Vaccination of Influenza A Virus in Swine.
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    Chapter 392 Swine and Influenza: A Challenge to One Health Research.
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    Chapter 393 Acid-Induced Membrane Fusion by the Hemagglutinin Protein and Its Role in Influenza Virus Biology
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    Chapter 394 Secondary Bacterial Infections in Influenza Virus Infection Pathogenesis
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    Chapter 395 Influenza A Virus Reassortment.
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    Chapter 396 Evolution and Ecology of Influenza A Viruses.
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    Chapter 419 Pandemic Preparedness and the Influenza Risk Assessment Tool (IRAT).
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    Chapter 422 Antigenic Analyses of Highly Pathogenic Avian Influenza A Viruses.
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    Chapter 423 Receptor Binding Properties of the Influenza Virus Hemagglutinin as a Determinant of Host Range
Attention for Chapter 390: Transmission in the Guinea Pig Model
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Chapter title
Transmission in the Guinea Pig Model
Chapter number 390
Book title
Influenza Pathogenesis and Control - Volume I
Published in
Current topics in microbiology and immunology, July 2014
DOI 10.1007/82_2014_390
Pubmed ID
Book ISBNs
978-3-31-911154-4, 978-3-31-911155-1

Anice C. Lowen, Nicole M. Bouvier, John Steel


The ability of an influenza virus to transmit efficiently from human-to-human is a major factor in determining the epidemiological impact of that strain. The use of a relevant animal model to identify viral determinants of transmission, as well as host and environmental factors affecting transmission efficiency, is therefore critical for public health. The characterization of newly emerging influenza viruses in terms of their potential to transmit in a mammalian host is furthermore an important part of pandemic risk assessment. For these reasons, a guinea pig model of influenza virus transmission was developed in 2006. The guinea pig provides an important alternative to preexisting models for influenza. Most influenza viruses do not readily transmit among mice. Ferrets, while highly relevant, are expensive and can be difficult to obtain in high numbers. Moreover, it is generally accepted that efforts to accurately model human disease are strengthened by the use of multiple animal species. Herein, we provide an overview of influenza virus infectivity, growth, and transmission in the guinea pig and highlight knowledge gained on the topic of influenza virus transmission using the guinea pig model.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 5%
Unknown 20 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 19%
Student > Master 4 19%
Researcher 3 14%
Student > Doctoral Student 2 10%
Librarian 2 10%
Other 3 14%
Unknown 3 14%
Readers by discipline Count As %
Medicine and Dentistry 6 29%
Agricultural and Biological Sciences 6 29%
Immunology and Microbiology 4 19%
Veterinary Science and Veterinary Medicine 2 10%
Unknown 3 14%

Attention Score in Context

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