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Mouse Models for Drug Discovery

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Cover of 'Mouse Models for Drug Discovery'

Table of Contents

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    Book Overview
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    Chapter 1 Improving Toxicity Screening and Drug Development by Using Genetically Defined Strains
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    Chapter 2 The Sophisticated Mouse: Protecting a Precious Reagent
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    Chapter 3 Genetically Engineered Mouse Models in Drug Discovery Research
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    Chapter 4 Engineering the Mouse Genome to Model Human Disease for Drug Discovery
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    Chapter 5 Profiling of drug action using reporter mice and molecular imaging.
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    Chapter 6 Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies
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    Chapter 7 Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease.
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    Chapter 8 Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans
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    Chapter 9 Mouse Models of Type II Diabetes Mellitus in Drug Discovery
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    Chapter 10 Cholesterol Absorption and Metabolism
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    Chapter 11 Collagen-Induced Arthritis in Mice
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    Chapter 12 Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening
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    Chapter 13 Models of Metastasis in Drug Discovery
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    Chapter 14 Methods for Evaluating Effects of an Irinotecan + 5-Fluorouracil/Leucovorin (IFL) Regimen in an Orthotopic Metastatic Colorectal Cancer Model Utilizing In Vivo Bioluminescence Imaging
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    Chapter 15 CML Mouse Model in Translational Research
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    Chapter 16 Mouse Models for Studying Depression-Like States and Antidepressant Drugs
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    Chapter 17 Virus-Delivered RNA Interference in Mouse Brain to Study Addiction-Related Behaviors
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    Chapter 18 Experimental Models of Anxiety for Drug Discovery and Brain Research
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    Chapter 19 Mouse Models of Neurodegenerative Diseases: Criteria and General Methodology
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    Chapter 20 Neuromuscular Disease Models and Analysis
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    Chapter 21 Murine Model of Cutaneous Infection with Streptococcus pyogenes
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    Chapter 22 Murine Model of Pneumococcal Pneumonia
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    Chapter 23 Murine Model of Polymicrobial Septic Peritonitis Using Cecal Ligation and Puncture (CLP)
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    Chapter 24 Erratum to: Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies
Overall attention for this book and its chapters
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Mouse Models for Drug Discovery
Published by
Humana Press, December 2009
DOI 10.1007/978-1-60761-058-8
978-1-60761-057-1, 978-1-60761-058-8

Proetzel, Gabriele, Wiles, Michael V.

Mendeley readers

The data shown below were compiled from readership statistics for 301 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 6 2%
Switzerland 2 <1%
Denmark 2 <1%
United Kingdom 2 <1%
Australia 1 <1%
Korea, Republic of 1 <1%
Brazil 1 <1%
France 1 <1%
Malaysia 1 <1%
Other 2 <1%
Unknown 282 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 86 29%
Student > Ph. D. Student 74 25%
Student > Master 28 9%
Student > Bachelor 18 6%
Student > Postgraduate 17 6%
Other 52 17%
Unknown 26 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 114 38%
Medicine and Dentistry 50 17%
Biochemistry, Genetics and Molecular Biology 43 14%
Immunology and Microbiology 14 5%
Neuroscience 12 4%
Other 29 10%
Unknown 39 13%