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Mouse Models for Drug Discovery

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Cover of 'Mouse Models for Drug Discovery'

Table of Contents

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    Book Overview
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    Chapter 1 Improving Toxicity Screening and Drug Development by Using Genetically Defined Strains
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    Chapter 2 The Sophisticated Mouse: Protecting a Precious Reagent
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    Chapter 3 Genetically Engineered Mouse Models in Drug Discovery Research
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    Chapter 4 Engineering the Mouse Genome to Model Human Disease for Drug Discovery
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    Chapter 5 Profiling of drug action using reporter mice and molecular imaging.
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    Chapter 6 Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies
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    Chapter 7 Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease.
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    Chapter 8 Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans
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    Chapter 9 Mouse Models of Type II Diabetes Mellitus in Drug Discovery
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    Chapter 10 Cholesterol Absorption and Metabolism
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    Chapter 11 Collagen-Induced Arthritis in Mice
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    Chapter 12 Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening
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    Chapter 13 Models of Metastasis in Drug Discovery
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    Chapter 14 Methods for Evaluating Effects of an Irinotecan + 5-Fluorouracil/Leucovorin (IFL) Regimen in an Orthotopic Metastatic Colorectal Cancer Model Utilizing In Vivo Bioluminescence Imaging
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    Chapter 15 CML Mouse Model in Translational Research
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    Chapter 16 Mouse Models for Studying Depression-Like States and Antidepressant Drugs
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    Chapter 17 Virus-Delivered RNA Interference in Mouse Brain to Study Addiction-Related Behaviors
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    Chapter 18 Experimental Models of Anxiety for Drug Discovery and Brain Research
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    Chapter 19 Mouse Models of Neurodegenerative Diseases: Criteria and General Methodology
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    Chapter 20 Neuromuscular Disease Models and Analysis
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    Chapter 21 Murine Model of Cutaneous Infection with Streptococcus pyogenes
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    Chapter 22 Murine Model of Pneumococcal Pneumonia
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    Chapter 23 Murine Model of Polymicrobial Septic Peritonitis Using Cecal Ligation and Puncture (CLP)
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    Chapter 24 Erratum to: Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies
Attention for Chapter 2: The Sophisticated Mouse: Protecting a Precious Reagent
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Chapter title
The Sophisticated Mouse: Protecting a Precious Reagent
Chapter number 2
Book title
Mouse Models for Drug Discovery
Published in
Methods in molecular biology, January 2010
DOI 10.1007/978-1-60761-058-8_2
Pubmed ID
Book ISBNs
978-1-60761-057-1, 978-1-60761-058-8
Authors

Michael V. Wiles, Rob A. Taft, Wiles, Michael V., Taft, Rob A.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 14%
Canada 1 5%
Unknown 18 82%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 27%
Student > Ph. D. Student 4 18%
Student > Bachelor 3 14%
Lecturer 2 9%
Other 2 9%
Other 4 18%
Unknown 1 5%
Readers by discipline Count As %
Medicine and Dentistry 6 27%
Agricultural and Biological Sciences 5 23%
Economics, Econometrics and Finance 4 18%
Biochemistry, Genetics and Molecular Biology 3 14%
Business, Management and Accounting 1 5%
Other 2 9%
Unknown 1 5%