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Notch Signaling

Overview of attention for book
Cover of 'Notch Signaling'

Table of Contents

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    Book Overview
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    Chapter 1 Introduction to notch signaling.
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    Chapter 2 Genetic screens to identify new notch pathway mutants in Drosophila.
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    Chapter 3 Structure-function analysis of Drosophila notch using genomic rescue transgenes.
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    Chapter 4 Overview of Genetic Tools and Techniques to Study Notch Signaling in Mice
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    Chapter 5 Immunohistochemical Tools and Techniques to Visualize Notch in Drosophila melanogaster.
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    Chapter 6 Antibody uptake assay and in vivo imaging to study intracellular trafficking of notch and delta in Drosophila.
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    Chapter 7 Tracking Trafficking of Notch and Its Ligands in Mammalian Cells
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    Chapter 8 Visualizing notch signaling in vivo in Drosophila tissues.
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    Chapter 9 Monitoring Notch Activity in the Mouse
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    Chapter 10 Notch signaling assays in Drosophila cultured cell lines.
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    Chapter 11 Monitoring Notch Activation in Cultured Mammalian Cells: Transcriptional Reporter Assays
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    Chapter 12 Monitoring notch activation in cultured Mammalian cells: luciferase complementation imaging assays.
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    Chapter 13 Visualization of Notch Signaling Oscillation in Cells and Tissues
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    Chapter 14 Proteomic analysis of the notch interactome.
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    Chapter 15 Bacterial Expression and In Vitro Refolding of Limited Fragments of the Notch Receptor and Its Ligands
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    Chapter 16 Analyzing the Posttranslational Modification Status of Notch Using Mass Spectrometry
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    Chapter 17 Assay to Probe Proteolytic Processing of Notch by γ-Secretase
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    Chapter 18 Analyzing the nuclear complexes of notch signaling by electrophoretic mobility shift assay.
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    Chapter 19 Identifying Direct Notch Transcriptional Targets Using the GSI-Washout Assay
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    Chapter 20 Probing the epigenetic status at notch target genes.
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    Chapter 21 Notch-ligand binding assays in Drosophila cells.
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    Chapter 22 Modeling notch signaling: a practical tutorial.
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    Chapter 23 Small Molecules That Inhibit Notch Signaling
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    Chapter 24 Application and Evaluation of Anti-Notch Antibodies to Modulate Notch Signaling
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    Chapter 25 Application of Anti-Ligand Antibodies to Inhibit Notch Signaling
Attention for Chapter 8: Visualizing notch signaling in vivo in Drosophila tissues.
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  • Good Attention Score compared to outputs of the same age and source (71st percentile)

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Chapter title
Visualizing notch signaling in vivo in Drosophila tissues.
Chapter number 8
Book title
Notch Signaling
Published in
Methods in molecular biology, January 2014
DOI 10.1007/978-1-4939-1139-4_8
Pubmed ID
Book ISBNs
978-1-4939-1138-7, 978-1-4939-1139-4
Authors

Benjamin E Housden, Jinghua Li, Sarah J Bray, Housden BE, Li J, Bray SJ, Benjamin E. Housden, Sarah J. Bray, Housden, Benjamin E., Li, Jinghua, Bray, Sarah J.

Abstract

The ability to visualize Notch pathway activity in vivo is invaluable for studying the functions and mechanisms of Notch signaling. A variety of tools have been developed to enable monitoring of pathway activity in Drosophila, including endogenous Notch-responsive genes and synthetic transcriptional reporter constructs. Here we summarize some of the different Notch signaling reporters that are available, discuss their relative merits, and describe two methods for visualizing their expression (immunostaining and X-gal staining). These approaches are widely applicable to a range of tissues and stages in Drosophila development.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 24%
Researcher 3 18%
Professor 2 12%
Lecturer 1 6%
Student > Master 1 6%
Other 1 6%
Unknown 5 29%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 35%
Biochemistry, Genetics and Molecular Biology 3 18%
Environmental Science 1 6%
Economics, Econometrics and Finance 1 6%
Neuroscience 1 6%
Other 0 0%
Unknown 5 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 July 2014.
All research outputs
#14,657,412
of 23,577,654 outputs
Outputs from Methods in molecular biology
#4,321
of 13,410 outputs
Outputs of similar age
#176,902
of 309,121 outputs
Outputs of similar age from Methods in molecular biology
#168
of 587 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,410 research outputs from this source. They receive a mean Attention Score of 3.4. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 309,121 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 587 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.