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Synthetic mRNA

Overview of attention for book
Cover of 'Synthetic mRNA'

Table of Contents

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    Book Overview
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    Chapter 1 Synthetic mRNA
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    Chapter 2 Synthetic Capped mRNAs for Cap-Specific Photo-Cross-Linking Experiments
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    Chapter 3 Enzymatic Modification of 5′-Capped RNA and Subsequent Labeling by Click Chemistry
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    Chapter 4 Preparation of Functional, Fluorescently Labeled mRNA Capped with Anthraniloyl-m 7 GpppG
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    Chapter 5 Intronless β -Globin Reporter: A Tool for Studying Nuclear RNA Stability Elements
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    Chapter 6 Synthetic mRNA
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    Chapter 7 Synthetic mRNA
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    Chapter 8 Synthetic mRNA
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    Chapter 9 Synthetic mRNA
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    Chapter 10 Synthetic mRNA
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    Chapter 11 Synthetic mRNA
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    Chapter 12 Synthetic mRNA
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    Chapter 13 Synthetic mRNA
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    Chapter 14 Transfection of Human Keratinocytes with Nucleoside-Modified mRNA Encoding CPD-Photolyase to Repair DNA Damage
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    Chapter 15 Synthetic mRNA
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    Chapter 16 Synthetic mRNA
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    Chapter 17 Synthetic mRNA
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    Chapter 18 Synthetic mRNA
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    Chapter 19 Synthetic mRNA
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    Chapter 20 Measuring Hematocrit in Mice Injected with In Vitro-Transcribed Erythropoietin mRNA
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    Chapter 21 Genetic Modification of Human Pancreatic Progenitor Cells Through Modified mRNA
Attention for Chapter 18: Synthetic mRNA
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Chapter title
Synthetic mRNA
Chapter number 18
Book title
Synthetic mRNA
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3625-0_18
Pubmed ID
27236806
Book ISBNs
978-1-4939-3623-6, 978-1-4939-3625-0
Authors

Coosemans, An, Tuyaerts, Sandra, Morias, Kim, Corthals, Jurgen, Heirman, Carlo, Thielemans, Kris, Van Gool, Stefaan W, Vergote, Ignace, Amant, Frédéric, An Coosemans, Sandra Tuyaerts, Kim Morias, Jurgen Corthals, Carlo Heirman, Kris Thielemans, Stefaan W. Van Gool, Ignace Vergote, Frédéric Amant, Gool, Stefaan W. Van

Abstract

The immune system is a crucial player in the development of cancer. Once it is in imbalance and immunosuppressive mechanisms supporting tumor growth take over control, dendritic cell immunotherapy might offer a solution to restore the balance. There are several methods to manufacture dendritic cells but none of them has yet proven to be superior to others. In this chapter, we discuss the methodology using electroporation of mRNA encoding Wilms' tumor gene 1, survivin, and TriMix (mixture of caTLR4, CD40L, and CD70) to simultaneously load and mature dendritic cells.

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X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 2 22%
Other 1 11%
Student > Doctoral Student 1 11%
Student > Master 1 11%
Researcher 1 11%
Other 1 11%
Unknown 2 22%
Readers by discipline Count As %
Immunology and Microbiology 3 33%
Agricultural and Biological Sciences 2 22%
Medicine and Dentistry 2 22%
Unknown 2 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 May 2016.
All research outputs
#15,376,252
of 22,875,477 outputs
Outputs from Methods in molecular biology
#5,351
of 13,131 outputs
Outputs of similar age
#230,972
of 393,689 outputs
Outputs of similar age from Methods in molecular biology
#544
of 1,471 outputs
Altmetric has tracked 22,875,477 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,131 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 393,689 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,471 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.

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