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Protein-Protein Interactions as New Drug Targets

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Cover of 'Protein-Protein Interactions as New Drug Targets'

Table of Contents

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    Book Overview
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    Chapter 1 A-Kinase Anchoring Proteins as the Basis for cAMP Signaling
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    Chapter 2 Arrestins as Multi-Functional Signaling Adaptors
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    Chapter 3 Role of Ena/VASP Proteins in Homeostasis and Disease
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    Chapter 4 Scaffold/Matrix Attachment Regions (S/MARs): Relevance for Disease and Therapy
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    Chapter 5 Clathrin/AP-2-Dependent Endocytosis: A Novel Playground for the Pharmacological Toolbox?
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    Chapter 6 PDE4 Associates with Different Scaffolding Proteins: Modulating Interactions as Treatment for Certain Diseases
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    Chapter 7 G-Protein-Coupled Receptor-Signaling Components in Membrane Raft and Caveolae Microdomains
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    Chapter 8 Protein Scaffolds, Lipid Domains and Substrate Recognition in Protein Kinase C Function: Implications for Rational Drug Design
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    Chapter 9 Compartmentalised MAPK Pathways
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    Chapter 10 Dynamic Protein Complexes Regulate NF-κB Signaling
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    Chapter 11 An oncogenic hub: beta-catenin as a molecular target for cancer therapeutics.
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    Chapter 12 A Toolkit for Real-Time Detection of cAMP: Insights into Compartmentalized Signaling
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    Chapter 13 Scaffolding Proteins in Cardiac Myocytes
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    Chapter 14 Molecular Architecture of Signal Complexes Regulating Immune Cell Function
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    Chapter 15 Scaffolding Proteins at the Postsynaptic Density: Shank as the Architectural Framework
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    Chapter 16 Domains Mediate Protein-Protein Interactions and Nucleate Protein Assemblies
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    Chapter 17 Proline-Rich Sequence Recognition Domains (PRD): Ligands, Function and Inhibition
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    Chapter 18 Chemical Inhibition Through Conformational Stabilization of Rho GTPase Effectors
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    Chapter 19 Pharmacological Interference with Protein-Protein Interactions Mediated by Coiled-Coil Motifs
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    Chapter 20 Protein-Protein Interactions as New Drug Targets
Attention for Chapter 20: Protein-Protein Interactions as New Drug Targets
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Chapter title
Protein-Protein Interactions as New Drug Targets
Chapter number 20
Book title
Protein-Protein Interactions as New Drug Targets
Published in
Handbook of experimental pharmacology, January 2008
DOI 10.1007/978-3-540-72843-6_20
Pubmed ID
Book ISBNs
978-3-54-072842-9, 978-3-54-072843-6
Authors

Hundsrucker, Christian, C. Hundsrucker, E. Klussmann, Hundsrucker, C., Klussmann, E.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 5%
United States 1 5%
Unknown 18 90%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 30%
Professor > Associate Professor 3 15%
Professor 2 10%
Student > Master 2 10%
Student > Bachelor 1 5%
Other 5 25%
Unknown 1 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 50%
Biochemistry, Genetics and Molecular Biology 4 20%
Medicine and Dentistry 3 15%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Neuroscience 1 5%
Other 0 0%
Unknown 1 5%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 August 2016.
All research outputs
#20,337,210
of 22,882,389 outputs
Outputs from Handbook of experimental pharmacology
#570
of 649 outputs
Outputs of similar age
#151,715
of 156,485 outputs
Outputs of similar age from Handbook of experimental pharmacology
#14
of 15 outputs
Altmetric has tracked 22,882,389 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 649 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 156,485 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.