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Protein-Protein Interactions as New Drug Targets

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Cover of 'Protein-Protein Interactions as New Drug Targets'

Table of Contents

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    Book Overview
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    Chapter 1 A-Kinase Anchoring Proteins as the Basis for cAMP Signaling
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    Chapter 2 Arrestins as Multi-Functional Signaling Adaptors
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    Chapter 3 Role of Ena/VASP Proteins in Homeostasis and Disease
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    Chapter 4 Scaffold/Matrix Attachment Regions (S/MARs): Relevance for Disease and Therapy
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    Chapter 5 Clathrin/AP-2-Dependent Endocytosis: A Novel Playground for the Pharmacological Toolbox?
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    Chapter 6 PDE4 Associates with Different Scaffolding Proteins: Modulating Interactions as Treatment for Certain Diseases
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    Chapter 7 G-Protein-Coupled Receptor-Signaling Components in Membrane Raft and Caveolae Microdomains
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    Chapter 8 Protein Scaffolds, Lipid Domains and Substrate Recognition in Protein Kinase C Function: Implications for Rational Drug Design
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    Chapter 9 Compartmentalised MAPK Pathways
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    Chapter 10 Dynamic Protein Complexes Regulate NF-κB Signaling
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    Chapter 11 An oncogenic hub: beta-catenin as a molecular target for cancer therapeutics.
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    Chapter 12 A Toolkit for Real-Time Detection of cAMP: Insights into Compartmentalized Signaling
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    Chapter 13 Scaffolding Proteins in Cardiac Myocytes
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    Chapter 14 Molecular Architecture of Signal Complexes Regulating Immune Cell Function
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    Chapter 15 Scaffolding Proteins at the Postsynaptic Density: Shank as the Architectural Framework
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    Chapter 16 Domains Mediate Protein-Protein Interactions and Nucleate Protein Assemblies
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    Chapter 17 Proline-Rich Sequence Recognition Domains (PRD): Ligands, Function and Inhibition
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    Chapter 18 Chemical Inhibition Through Conformational Stabilization of Rho GTPase Effectors
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    Chapter 19 Pharmacological Interference with Protein-Protein Interactions Mediated by Coiled-Coil Motifs
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    Chapter 20 Protein-Protein Interactions as New Drug Targets
Attention for Chapter 18: Chemical Inhibition Through Conformational Stabilization of Rho GTPase Effectors
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Citations

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Chapter title
Chemical Inhibition Through Conformational Stabilization of Rho GTPase Effectors
Chapter number 18
Book title
Protein-Protein Interactions as New Drug Targets
Published by
Springer, Berlin, Heidelberg, January 2008
DOI 10.1007/978-3-540-72843-6_18
Pubmed ID
18491063
Book ISBNs
978-3-54-072842-9, 978-3-54-072843-6
Authors

S. W. Deacon, J. R. Peterson, Deacon, S. W., Peterson, J. R.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Philippines 1 3%
Unknown 28 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 38%
Student > Ph. D. Student 4 14%
Lecturer > Senior Lecturer 2 7%
Student > Master 2 7%
Professor > Associate Professor 2 7%
Other 2 7%
Unknown 6 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 38%
Medicine and Dentistry 5 17%
Biochemistry, Genetics and Molecular Biology 4 14%
Business, Management and Accounting 1 3%
Immunology and Microbiology 1 3%
Other 1 3%
Unknown 6 21%

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