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Protein-Protein Interactions as New Drug Targets

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Table of Contents

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    Book Overview
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    Chapter 1 A-Kinase Anchoring Proteins as the Basis for cAMP Signaling
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    Chapter 2 Arrestins as Multi-Functional Signaling Adaptors
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    Chapter 3 Role of Ena/VASP Proteins in Homeostasis and Disease
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    Chapter 4 Scaffold/Matrix Attachment Regions (S/MARs): Relevance for Disease and Therapy
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    Chapter 5 Clathrin/AP-2-Dependent Endocytosis: A Novel Playground for the Pharmacological Toolbox?
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    Chapter 6 PDE4 Associates with Different Scaffolding Proteins: Modulating Interactions as Treatment for Certain Diseases
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    Chapter 7 G-Protein-Coupled Receptor-Signaling Components in Membrane Raft and Caveolae Microdomains
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    Chapter 8 Protein Scaffolds, Lipid Domains and Substrate Recognition in Protein Kinase C Function: Implications for Rational Drug Design
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    Chapter 9 Compartmentalised MAPK Pathways
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    Chapter 10 Dynamic Protein Complexes Regulate NF-κB Signaling
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    Chapter 11 An oncogenic hub: beta-catenin as a molecular target for cancer therapeutics.
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    Chapter 12 A Toolkit for Real-Time Detection of cAMP: Insights into Compartmentalized Signaling
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    Chapter 13 Scaffolding Proteins in Cardiac Myocytes
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    Chapter 14 Molecular Architecture of Signal Complexes Regulating Immune Cell Function
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    Chapter 15 Scaffolding Proteins at the Postsynaptic Density: Shank as the Architectural Framework
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    Chapter 16 Domains Mediate Protein-Protein Interactions and Nucleate Protein Assemblies
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    Chapter 17 Proline-Rich Sequence Recognition Domains (PRD): Ligands, Function and Inhibition
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    Chapter 18 Chemical Inhibition Through Conformational Stabilization of Rho GTPase Effectors
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    Chapter 19 Pharmacological Interference with Protein-Protein Interactions Mediated by Coiled-Coil Motifs
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    Chapter 20 Protein-Protein Interactions as New Drug Targets
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