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Oxygen Transport to Tissue XXXIV

Overview of attention for book
Cover of 'Oxygen Transport to Tissue XXXIV'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Effects of Experimentally Deviated Mandibular Position on Stress Response
  3. Altmetric Badge
    Chapter 2 Kidney EPO Expression During Chronic Hypoxia in Aged Mice
  4. Altmetric Badge
    Chapter 3 Nature’s “Silver Bullet” for Anticoagulation: Mechanism of Zymogen Protein C to Activated Protein C
  5. Altmetric Badge
    Chapter 4 Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO
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    Chapter 5 Blood Oxygen Level Dependent Magnetization Transfer (BOLDMT) Effect
  7. Altmetric Badge
    Chapter 6 Characterizing Prostate Tumor Mouse Xenografts with CEST and MT-MRI and Redox Scanning.
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    Chapter 7 In Vitro Sirius Red Collagen Assay Measures the Pattern Shift from Soluble to Deposited Collagen
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    Chapter 8 Intravoxel Incoherent Motion MR Imaging of the Kidney: Pilot Study
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    Chapter 9 Changes in Gastric Mucosa, Submucosa, and Muscularis IC pH May Herald Irreversible Tissue Injury
  11. Altmetric Badge
    Chapter 10 Oxygen Transport to Tissue XXXIV
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    Chapter 11 Multi-frequency Forced Oscillation Technique Using Impulse Oscillations: Can It Give Mechanical Information about the Lung Periphery?
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    Chapter 12 NIRS Measurements with Elite Speed Skaters: Comparison Between the Ice Rink and the Laboratory.
  14. Altmetric Badge
    Chapter 13 Oxygen Transport to Tissue XXXIV
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    Chapter 14 Oxygen Delivery Deficit in Exercise with Rapid Ascent to High Altitude
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    Chapter 15 Oxygen Transport to Tissue XXXIV
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    Chapter 16 Effect of spinal anesthesia for elective cesarean section on cerebral blood oxygenation changes: comparison of hyperbaric and isobaric bupivacaine.
  18. Altmetric Badge
    Chapter 17 DCX-Expressing Neurons Decrease in the Retrosplenial Cortex after Global Brain Ischemia
  19. Altmetric Badge
    Chapter 18 Calibration and Validation Scheme for In Vivo Spectroscopic Imaging of Tissue Oxygenation
  20. Altmetric Badge
    Chapter 19 Considering the Vascular Hypothesis of Alzheimer’s Disease: Effect of Copper Associated Amyloid on Red Blood Cells
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    Chapter 20 The Role of Mitochondrial Proteomic Analysis in Radiological Accidents and Terrorism
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    Chapter 21 Alteration of Plasma Galactose/ N -acetylgalactosamine Level After Irradiation
  23. Altmetric Badge
    Chapter 22 Fibroblast Growth Factor-Peptide Promotes Bone Marrow Recovery After Irradiation
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    Chapter 23 Dynamic Two-Photon Imaging of Cerebral Microcirculation Using Fluorescently Labeled Red Blood Cells and Plasma
  25. Altmetric Badge
    Chapter 24 The Effect of Basic Assumptions on the Tissue Oxygen Saturation Value of Near Infrared Spectroscopy
  26. Altmetric Badge
    Chapter 25 The effect of sudden depressurization on pilots at cruising altitude.
  27. Altmetric Badge
    Chapter 26 Hypoxia in the diabetic kidney is independent of advanced glycation end-products.
  28. Altmetric Badge
    Chapter 27 Tumor Oxygen Measurements and Personalized Medicine
  29. Altmetric Badge
    Chapter 28 Wavelet Cross-Correlation to Investigate Regional Variations in Cerebral Oxygenation in Infants Supported on Extracorporeal Membrane Oxygenation
  30. Altmetric Badge
    Chapter 29 Association of the Red Cell Distribution Width with Red Blood Cell Deformability
  31. Altmetric Badge
    Chapter 30 Kidney Function After In Vivo Gene Silencing of Uncoupling Protein-2 in Streptozotocin-Induced Diabetic Rats
  32. Altmetric Badge
    Chapter 31 Adenosine A2 receptor-mediated regulation of renal hemodynamics and glomerular filtration rate is abolished in diabetes.
  33. Altmetric Badge
    Chapter 32 Can Mitochondrial Cytochrome Oxidase Mediate Hypoxic Vasodilation Via Nitric Oxide Metabolism?
  34. Altmetric Badge
    Chapter 33 Effects of Occlusal Disharmony on Working Memory Performance and Prefrontal Cortex Activity Induced by Working Memory Tasks Measured by NIRS
  35. Altmetric Badge
    Chapter 34 Biological maintenance of distal vein arterialization.
  36. Altmetric Badge
    Chapter 35 Bayesian STAI Anxiety Index Predictions Based on Prefrontal Cortex NIRS Data for the Resting State
  37. Altmetric Badge
    Chapter 36 The Effect of Venous and Arterial Occlusion of the Arm on Changes in Tissue Hemodynamics, Oxygenation, and Ultra-Weak Photon Emission
  38. Altmetric Badge
    Chapter 37 Metabolic Network Analysis of DB1 Melanoma Cells: How Much Energy Is Derived from Aerobic Glycolysis?
  39. Altmetric Badge
    Chapter 38 Muscle Oxygen Saturation Heterogeneity Among Leg Muscles During Ramp Exercise
  40. Altmetric Badge
    Chapter 39 PET Imaging of the Impact of Extracellular pH and MAP Kinases on the p -Glycoprotein (Pgp) Activity
  41. Altmetric Badge
    Chapter 40 Meconium and Transitional Stools May Cause Interference with Near-Infrared Spectroscopy Measurements of Intestinal Oxygen Saturation in Preterm Infants
  42. Altmetric Badge
    Chapter 41 Acute effects of physical exercise on prefrontal cortex activity in older adults: a functional near-infrared spectroscopy study.
  43. Altmetric Badge
    Chapter 42 Blood Flow and Oxygenation Status of Prostate Cancers
  44. Altmetric Badge
    Chapter 43 Targeted delivery of VEGF to treat myocardial infarction.
  45. Altmetric Badge
    Chapter 44 Magnetic Nanoparticles and Thermally Responsive Polymer for Targeted Hyperthermia and Sustained Anti-Cancer Drug Delivery
  46. Altmetric Badge
    Chapter 45 NIR Fluorophore-Hollow Gold Nanosphere Complex for Cancer Enzyme-Triggered Detection and Hyperthermia
  47. Altmetric Badge
    Chapter 46 Renal Oxygenation and Function of the Rat Kidney: Effects of Inspired Oxygen and Preglomerular Oxygen Shunting
  48. Altmetric Badge
    Chapter 47 Alteration of the Inflammatory Molecule Network After Irradiation of Soft Tissue
  49. Altmetric Badge
    Chapter 48 Imaging the redox States of human breast cancer core biopsies.
  50. Altmetric Badge
    Chapter 49 Early Life Hypoxic or Hypoxic/Hypercapnic Stress Alters Acute Ventilatory Sensitivity in Adult Mice
  51. Altmetric Badge
    Chapter 50 3D Analysis of Intracortical Microvasculature During Chronic Hypoxia in Mouse Brains
  52. Altmetric Badge
    Chapter 51 Contribution of Brain Glucose and Ketone Bodies to Oxidative Metabolism
  53. Altmetric Badge
    Chapter 52 Alteration of Circulating Mitochondrial DNA Concentration After Irradiation
  54. Altmetric Badge
    Chapter 53 Erratum to: Oxygen Transport to Tissue XXXIV
Attention for Chapter 26: Hypoxia in the diabetic kidney is independent of advanced glycation end-products.
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Chapter title
Hypoxia in the diabetic kidney is independent of advanced glycation end-products.
Chapter number 26
Book title
Oxygen Transport to Tissue XXXIV
Published in
Advances in experimental medicine and biology, August 2012
DOI 10.1007/978-1-4614-4989-8_26
Pubmed ID
Book ISBNs
978-1-4614-4771-9, 978-1-4614-4989-8

Nordquist L, Liss P, Fasching A, Hansell P, Palm F, Lina Nordquist, Per Liss, Angelica Fasching, Peter Hansell, Fredrik Palm


Sustained hyperglycemia is closely associated with increased risk to develop nephropathy. We have previously reported alterations in the intrarenal oxygen metabolism already after the early onset of diabetes. Furthermore, formation of advanced glycation end-products (AGE) is postulated as a major contributor to diabetic nephropathy. We therefore investigated the possible relationship between altered oxygen metabolism and AGE in diabetic kidneys.Normoglycemic and streptozotocin-diabetic rats with and without chronic treatment with aminoguanidine (AGE inhibitor; 600 mg/kg bw/24 h in drinking water) or L-N(6)-(1-Iminoethyl)lysine (L-NIL, iNOS inhibitor, 1 mg/kg bw/24 h in drinking water) were studied 2 weeks after induction of diabetes. Glomerular filtration rate (GFR) was estimated by inulin clearance, oxygen tension (pO(2)) and interstitial pH by microelectrodes and regional renal blood flow (RBF) by laser-Doppler. Histological changes were evaluated on fixed tissue.Glomerular hyperfiltration was unaffected by aminoguanidine, whereas L-NIL normalized GFR in diabetic rats. pO(2) and interstitial pH, but not RBF, were lower in both kidney cortex and medulla compared to control rats, but was unaffected by both chronic treatments. Urinary protein excretion was higher in diabetic rats and unaffected by L-NIL, whereas aminoguanidine paradoxically increased this parameter. Damage scores were similar in all groups.In conclusion, diabetes-induced alterations in intrarenal oxygen metabolism are independent of the AGE pathway, and precede any morphological changes. These findings highlight the early stage of diabetes as being a metabolic disorder also in the kidney.

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Mendeley readers

The data shown below were compiled from readership statistics for 3 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 3 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 33%
Professor > Associate Professor 1 33%
Unknown 1 33%
Readers by discipline Count As %
Immunology and Microbiology 1 33%
Chemistry 1 33%
Unknown 1 33%

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