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Mendeley readers
Chapter title |
Cell Biology Approaches to Studying Prion Diseases
|
---|---|
Chapter number | 7 |
Book title |
Prions
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Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-7244-9_7 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7242-5, 978-1-4939-7244-9
|
Authors |
Suzette A. Priola, Priola, Suzette A. |
Abstract |
During the course of prion infection, the normally soluble and protease-sensitive mammalian prion protein (PrP(C)) is refolded into an insoluble, partially protease-resistant, and infectious form called PrP(Sc). The conformational conversion of PrP(C) to PrP(Sc) is a critical event during prion infection and is essential for the production of prion infectivity. This chapter briefly summarizes the ways in which cell biological approaches have enhanced our understanding of how PrP contributes to different aspects of prion pathogenesis. |
Mendeley readers
The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 5 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 2 | 40% |
Researcher | 1 | 20% |
Unknown | 2 | 40% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 1 | 20% |
Biochemistry, Genetics and Molecular Biology | 1 | 20% |
Immunology and Microbiology | 1 | 20% |
Unknown | 2 | 40% |